Micro-Macro Coupling for Optimizing Scaffold Mediated Bone Regeneration

Fuente: arXiv
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Main Authors: Dondl, Patrick, Suchan, Oliver
Format: Preprint
Published: 2025
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_version_ 1866910890325966848
author Dondl, Patrick
Suchan, Oliver
author_facet Dondl, Patrick
Suchan, Oliver
contents This work presents a framework for modeling three-dimensional scaffold-mediated bone regeneration and the associated optimization problem. By incorporating microstructure into the model through periodic homogenization, we capture the effects of microscale fluctuations on the bone growth process. Numerical results and optimized scaffold designs that explicitly account for the microstructure are presented, demonstrating the potential of this approach for improving scaffold performance.
format Preprint
id arxiv_https___arxiv_org_abs_2503_18795
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Micro-Macro Coupling for Optimizing Scaffold Mediated Bone Regeneration
Dondl, Patrick
Suchan, Oliver
Numerical Analysis
68Q25, 68R10, 68U05
This work presents a framework for modeling three-dimensional scaffold-mediated bone regeneration and the associated optimization problem. By incorporating microstructure into the model through periodic homogenization, we capture the effects of microscale fluctuations on the bone growth process. Numerical results and optimized scaffold designs that explicitly account for the microstructure are presented, demonstrating the potential of this approach for improving scaffold performance.
title Micro-Macro Coupling for Optimizing Scaffold Mediated Bone Regeneration
topic Numerical Analysis
68Q25, 68R10, 68U05
url https://arxiv.org/abs/2503.18795