Foundation Model for Whole-Heart Segmentation: Leveraging Student-Teacher Learning in Multi-Modal Medical Imaging

Fuente: arXiv
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Autores principales: Qayyum, Abdul, Mazher, Moona, Ugurlu, Devran, Lemus, Jose Alonso Solis, Rodero, Cristobal, Niederer, Steven A
Formato: Preprint
Publicado: 2025
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author Qayyum, Abdul
Mazher, Moona
Ugurlu, Devran
Lemus, Jose Alonso Solis
Rodero, Cristobal
Niederer, Steven A
author_facet Qayyum, Abdul
Mazher, Moona
Ugurlu, Devran
Lemus, Jose Alonso Solis
Rodero, Cristobal
Niederer, Steven A
contents Whole-heart segmentation from CT and MRI scans is crucial for cardiovascular disease analysis, yet existing methods struggle with modality-specific biases and the need for extensive labeled datasets. To address these challenges, we propose a foundation model for whole-heart segmentation using a self-supervised learning (SSL) framework based on a student-teacher architecture. Our model is pretrained on a large, unlabeled dataset of CT and MRI scans, leveraging the xLSTM backbone to capture long-range spatial dependencies and complex anatomical structures in 3D medical images. By incorporating multi-modal pretraining, our approach ensures strong generalization across both CT and MRI modalities, mitigating modality-specific variations and improving segmentation accuracy in diverse clinical settings. The use of large-scale unlabeled data significantly reduces the dependency on manual annotations, enabling robust performance even with limited labeled data. We further introduce an xLSTM-UNet-based architecture for downstream whole-heart segmentation tasks, demonstrating its effectiveness on few-label CT and MRI datasets. Our results validate the robustness and adaptability of the proposed model, highlighting its potential for advancing automated whole-heart segmentation in medical imaging.
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institution arXiv
publishDate 2025
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spellingShingle Foundation Model for Whole-Heart Segmentation: Leveraging Student-Teacher Learning in Multi-Modal Medical Imaging
Qayyum, Abdul
Mazher, Moona
Ugurlu, Devran
Lemus, Jose Alonso Solis
Rodero, Cristobal
Niederer, Steven A
Image and Video Processing
Computer Vision and Pattern Recognition
Whole-heart segmentation from CT and MRI scans is crucial for cardiovascular disease analysis, yet existing methods struggle with modality-specific biases and the need for extensive labeled datasets. To address these challenges, we propose a foundation model for whole-heart segmentation using a self-supervised learning (SSL) framework based on a student-teacher architecture. Our model is pretrained on a large, unlabeled dataset of CT and MRI scans, leveraging the xLSTM backbone to capture long-range spatial dependencies and complex anatomical structures in 3D medical images. By incorporating multi-modal pretraining, our approach ensures strong generalization across both CT and MRI modalities, mitigating modality-specific variations and improving segmentation accuracy in diverse clinical settings. The use of large-scale unlabeled data significantly reduces the dependency on manual annotations, enabling robust performance even with limited labeled data. We further introduce an xLSTM-UNet-based architecture for downstream whole-heart segmentation tasks, demonstrating its effectiveness on few-label CT and MRI datasets. Our results validate the robustness and adaptability of the proposed model, highlighting its potential for advancing automated whole-heart segmentation in medical imaging.
title Foundation Model for Whole-Heart Segmentation: Leveraging Student-Teacher Learning in Multi-Modal Medical Imaging
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2503.19005