Brain Organoid Computing -- an Overview

Fuente: arXiv
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Autores principales: Talavera, Yannic, Ulmann, Bernd
Formato: Preprint
Publicado: 2025
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author Talavera, Yannic
Ulmann, Bernd
author_facet Talavera, Yannic
Ulmann, Bernd
contents The aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive bibliography covering all relevant aspects and questions on this topic. Brain organoids - three-dimensional in vitro neural structures derived from human stem cells - have recently garnered attention not only in medical research but also as potential substrates for unconventional computing. Their biological nature allows them to exhibit learning behavior, plasticity, and parallel information processing, making them fundamentally different from traditional silicon-based systems. This opens up new perspectives on how intelligent systems might be designed in the future. Using brain organoids for computing presents a possible pathway towards more adaptive, energy-efficient, and biologically inspired forms of AI. However, challenges persist, particularly regarding lifespan, interfacing, reproducibility, and ethical concerns regarding the use of human-derived tissue. This paper aims to provide a foundational understanding for researchers exploring the convergence of human biology and computation.
format Preprint
id arxiv_https___arxiv_org_abs_2503_19770
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Brain Organoid Computing -- an Overview
Talavera, Yannic
Ulmann, Bernd
Emerging Technologies
I.2.m; B.m
The aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive bibliography covering all relevant aspects and questions on this topic. Brain organoids - three-dimensional in vitro neural structures derived from human stem cells - have recently garnered attention not only in medical research but also as potential substrates for unconventional computing. Their biological nature allows them to exhibit learning behavior, plasticity, and parallel information processing, making them fundamentally different from traditional silicon-based systems. This opens up new perspectives on how intelligent systems might be designed in the future. Using brain organoids for computing presents a possible pathway towards more adaptive, energy-efficient, and biologically inspired forms of AI. However, challenges persist, particularly regarding lifespan, interfacing, reproducibility, and ethical concerns regarding the use of human-derived tissue. This paper aims to provide a foundational understanding for researchers exploring the convergence of human biology and computation.
title Brain Organoid Computing -- an Overview
topic Emerging Technologies
I.2.m; B.m
url https://arxiv.org/abs/2503.19770