Attention Xception UNet (AXUNet): A Novel Combination of CNN and Self-Attention for Brain Tumor Segmentation

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Hauptverfasser: Moodi, Farzan, Shoushtari, Fereshteh Khodadadi, Valizadeh, Gelareh, Mazinani, Dornaz, Salari, Hanieh Mobarak, Rad, Hamidreza Saligheh
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Veröffentlicht: 2025
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author Moodi, Farzan
Shoushtari, Fereshteh Khodadadi
Valizadeh, Gelareh
Mazinani, Dornaz
Salari, Hanieh Mobarak
Rad, Hamidreza Saligheh
author_facet Moodi, Farzan
Shoushtari, Fereshteh Khodadadi
Valizadeh, Gelareh
Mazinani, Dornaz
Salari, Hanieh Mobarak
Rad, Hamidreza Saligheh
contents Accurate segmentation of glioma brain tumors is crucial for diagnosis and treatment planning. Deep learning techniques offer promising solutions, but optimal model architectures remain under investigation. We used the BraTS 2021 dataset, selecting T1 with contrast enhancement (T1CE), T2, and Fluid-Attenuated Inversion Recovery (FLAIR) sequences for model development. The proposed Attention Xception UNet (AXUNet) architecture integrates an Xception backbone with dot-product self-attention modules, inspired by state-of-the-art (SOTA) large language models such as Google Bard and OpenAI ChatGPT, within a UNet-shaped model. We compared AXUNet with SOTA models. Comparative evaluation on the test set demonstrated improved results over baseline models. Inception-UNet and Xception-UNet achieved mean Dice scores of 90.88 and 93.24, respectively. Attention ResUNet (AResUNet) attained a mean Dice score of 92.80, with the highest score of 84.92 for enhancing tumor (ET) among all models. Attention Gate UNet (AGUNet) yielded a mean Dice score of 90.38. AXUNet outperformed all models with a mean Dice score of 93.73. It demonstrated superior Dice scores across whole tumor (WT) and tumor core (TC) regions, achieving 92.59 for WT, 86.81 for TC, and 84.89 for ET. The integration of the Xception backbone and dot-product self-attention mechanisms in AXUNet showcases enhanced performance in capturing spatial and contextual information. The findings underscore the potential utility of AXUNet in facilitating precise tumor delineation.
format Preprint
id arxiv_https___arxiv_org_abs_2503_20446
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Attention Xception UNet (AXUNet): A Novel Combination of CNN and Self-Attention for Brain Tumor Segmentation
Moodi, Farzan
Shoushtari, Fereshteh Khodadadi
Valizadeh, Gelareh
Mazinani, Dornaz
Salari, Hanieh Mobarak
Rad, Hamidreza Saligheh
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Accurate segmentation of glioma brain tumors is crucial for diagnosis and treatment planning. Deep learning techniques offer promising solutions, but optimal model architectures remain under investigation. We used the BraTS 2021 dataset, selecting T1 with contrast enhancement (T1CE), T2, and Fluid-Attenuated Inversion Recovery (FLAIR) sequences for model development. The proposed Attention Xception UNet (AXUNet) architecture integrates an Xception backbone with dot-product self-attention modules, inspired by state-of-the-art (SOTA) large language models such as Google Bard and OpenAI ChatGPT, within a UNet-shaped model. We compared AXUNet with SOTA models. Comparative evaluation on the test set demonstrated improved results over baseline models. Inception-UNet and Xception-UNet achieved mean Dice scores of 90.88 and 93.24, respectively. Attention ResUNet (AResUNet) attained a mean Dice score of 92.80, with the highest score of 84.92 for enhancing tumor (ET) among all models. Attention Gate UNet (AGUNet) yielded a mean Dice score of 90.38. AXUNet outperformed all models with a mean Dice score of 93.73. It demonstrated superior Dice scores across whole tumor (WT) and tumor core (TC) regions, achieving 92.59 for WT, 86.81 for TC, and 84.89 for ET. The integration of the Xception backbone and dot-product self-attention mechanisms in AXUNet showcases enhanced performance in capturing spatial and contextual information. The findings underscore the potential utility of AXUNet in facilitating precise tumor delineation.
title Attention Xception UNet (AXUNet): A Novel Combination of CNN and Self-Attention for Brain Tumor Segmentation
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2503.20446