TAMA: A Human-AI Collaborative Thematic Analysis Framework Using Multi-Agent LLMs for Clinical Interviews

Fuente: arXiv
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Auteurs principaux: Xu, Huimin, Yi, Seungjun, Lim, Terence, Xu, Jiawei, Well, Andrew, Mery, Carlos, Zhang, Aidong, Zhang, Yuji, Ji, Heng, Pingali, Keshav, Leng, Yan, Ding, Ying
Format: Preprint
Publié: 2025
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author Xu, Huimin
Yi, Seungjun
Lim, Terence
Xu, Jiawei
Well, Andrew
Mery, Carlos
Zhang, Aidong
Zhang, Yuji
Ji, Heng
Pingali, Keshav
Leng, Yan
Ding, Ying
author_facet Xu, Huimin
Yi, Seungjun
Lim, Terence
Xu, Jiawei
Well, Andrew
Mery, Carlos
Zhang, Aidong
Zhang, Yuji
Ji, Heng
Pingali, Keshav
Leng, Yan
Ding, Ying
contents Thematic analysis (TA) is a widely used qualitative approach for uncovering latent meanings in unstructured text data. TA provides valuable insights in healthcare but is resource-intensive. Large Language Models (LLMs) have been introduced to perform TA, yet their applications in healthcare remain unexplored. Here, we propose TAMA: A Human-AI Collaborative Thematic Analysis framework using Multi-Agent LLMs for clinical interviews. We leverage the scalability and coherence of multi-agent systems through structured conversations between agents and coordinate the expertise of cardiac experts in TA. Using interview transcripts from parents of children with Anomalous Aortic Origin of a Coronary Artery (AAOCA), a rare congenital heart disease, we demonstrate that TAMA outperforms existing LLM-assisted TA approaches, achieving higher thematic hit rate, coverage, and distinctiveness. TAMA demonstrates strong potential for automated TA in clinical settings by leveraging multi-agent LLM systems with human-in-the-loop integration by enhancing quality while significantly reducing manual workload.
format Preprint
id arxiv_https___arxiv_org_abs_2503_20666
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle TAMA: A Human-AI Collaborative Thematic Analysis Framework Using Multi-Agent LLMs for Clinical Interviews
Xu, Huimin
Yi, Seungjun
Lim, Terence
Xu, Jiawei
Well, Andrew
Mery, Carlos
Zhang, Aidong
Zhang, Yuji
Ji, Heng
Pingali, Keshav
Leng, Yan
Ding, Ying
Human-Computer Interaction
Computation and Language
Thematic analysis (TA) is a widely used qualitative approach for uncovering latent meanings in unstructured text data. TA provides valuable insights in healthcare but is resource-intensive. Large Language Models (LLMs) have been introduced to perform TA, yet their applications in healthcare remain unexplored. Here, we propose TAMA: A Human-AI Collaborative Thematic Analysis framework using Multi-Agent LLMs for clinical interviews. We leverage the scalability and coherence of multi-agent systems through structured conversations between agents and coordinate the expertise of cardiac experts in TA. Using interview transcripts from parents of children with Anomalous Aortic Origin of a Coronary Artery (AAOCA), a rare congenital heart disease, we demonstrate that TAMA outperforms existing LLM-assisted TA approaches, achieving higher thematic hit rate, coverage, and distinctiveness. TAMA demonstrates strong potential for automated TA in clinical settings by leveraging multi-agent LLM systems with human-in-the-loop integration by enhancing quality while significantly reducing manual workload.
title TAMA: A Human-AI Collaborative Thematic Analysis Framework Using Multi-Agent LLMs for Clinical Interviews
topic Human-Computer Interaction
Computation and Language
url https://arxiv.org/abs/2503.20666