Evaluation of Machine-generated Biomedical Images via A Tally-based Similarity Measure

Fuente: arXiv
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Main Authors: Brooks, Frank J., Deshpande, Rucha
Format: Preprint
Published: 2025
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author Brooks, Frank J.
Deshpande, Rucha
author_facet Brooks, Frank J.
Deshpande, Rucha
contents Super-resolution, in-painting, whole-image generation, unpaired style-transfer, and network-constrained image reconstruction each include an aspect of machine-learned image synthesis where the actual ground truth is not known at time of use. It is generally difficult to quantitatively and authoritatively evaluate the quality of synthetic images; however, in mission-critical biomedical scenarios robust evaluation is paramount. In this work, all practical image-to-image comparisons really are relative qualifications, not absolute difference quantifications; and, therefore, meaningful evaluation of generated image quality can be accomplished using the Tversky Index, which is a well-established measure for assessing perceptual similarity. This evaluation procedure is developed and then demonstrated using multiple image data sets, both real and simulated. The main result is that when the subjectivity and intrinsic deficiencies of any feature-encoding choice are put upfront, Tversky's method leads to intuitive results, whereas traditional methods based on summarizing distances in deep feature spaces do not.
format Preprint
id arxiv_https___arxiv_org_abs_2503_22658
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Evaluation of Machine-generated Biomedical Images via A Tally-based Similarity Measure
Brooks, Frank J.
Deshpande, Rucha
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Machine Learning
Super-resolution, in-painting, whole-image generation, unpaired style-transfer, and network-constrained image reconstruction each include an aspect of machine-learned image synthesis where the actual ground truth is not known at time of use. It is generally difficult to quantitatively and authoritatively evaluate the quality of synthetic images; however, in mission-critical biomedical scenarios robust evaluation is paramount. In this work, all practical image-to-image comparisons really are relative qualifications, not absolute difference quantifications; and, therefore, meaningful evaluation of generated image quality can be accomplished using the Tversky Index, which is a well-established measure for assessing perceptual similarity. This evaluation procedure is developed and then demonstrated using multiple image data sets, both real and simulated. The main result is that when the subjectivity and intrinsic deficiencies of any feature-encoding choice are put upfront, Tversky's method leads to intuitive results, whereas traditional methods based on summarizing distances in deep feature spaces do not.
title Evaluation of Machine-generated Biomedical Images via A Tally-based Similarity Measure
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2503.22658