Effects of Geometric Modelling and Blood Rheology in Patient-Specific Arterial Blood Flow Simulations with Speed-Accuracy Trade-Off Analysis

Fuente: arXiv
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Autores principales: Kumar, Rishi, Muralidhar, K., Dalal, Indranil Saha
Formato: Preprint
Publicado: 2025
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author Kumar, Rishi
Muralidhar, K.
Dalal, Indranil Saha
author_facet Kumar, Rishi
Muralidhar, K.
Dalal, Indranil Saha
contents This study investigates the effects of geometric model reduction on blood flow simulations in the patient-specific descending aorta, followed by speed-accuracy trade-off analysis using 3D simulations. We demonstrate how wall shear stresses (WSS) can be reliably estimated for such realistic arteries using significantly faster simulations of highly idealized equivalent geometries, for any blood rheology model. CFD simulations (3D) are performed at two levels of geometry reduction employing realistic pulsatile inflow and pressure outlet boundary conditions and utilizing both Newtonian and non-Newtonian blood rheology models, including the one developed recently by Apostolidis and Beris. The first level of reduction does not retain effects due to local asymmetry but can approximate various flow parameters and patterns, while showing a significant computational speedup. However, further simplification to an idealized smooth geometry loses all information about the vortex structures and flow circulation. The non-Newtonian models retain more accuracy than the Newtonian models in geometry reductions, as quantified by correlations defined in this study. The idealized smooth geometry, combined with area correction, yields WSS estimates that closely approximate those of the actual artery. This study is expected to be applicable in geometric reductions (and speed enhancements) for more complex patient-specific 3D simulations while maintaining accuracy.
format Preprint
id arxiv_https___arxiv_org_abs_2503_23049
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Effects of Geometric Modelling and Blood Rheology in Patient-Specific Arterial Blood Flow Simulations with Speed-Accuracy Trade-Off Analysis
Kumar, Rishi
Muralidhar, K.
Dalal, Indranil Saha
Fluid Dynamics
This study investigates the effects of geometric model reduction on blood flow simulations in the patient-specific descending aorta, followed by speed-accuracy trade-off analysis using 3D simulations. We demonstrate how wall shear stresses (WSS) can be reliably estimated for such realistic arteries using significantly faster simulations of highly idealized equivalent geometries, for any blood rheology model. CFD simulations (3D) are performed at two levels of geometry reduction employing realistic pulsatile inflow and pressure outlet boundary conditions and utilizing both Newtonian and non-Newtonian blood rheology models, including the one developed recently by Apostolidis and Beris. The first level of reduction does not retain effects due to local asymmetry but can approximate various flow parameters and patterns, while showing a significant computational speedup. However, further simplification to an idealized smooth geometry loses all information about the vortex structures and flow circulation. The non-Newtonian models retain more accuracy than the Newtonian models in geometry reductions, as quantified by correlations defined in this study. The idealized smooth geometry, combined with area correction, yields WSS estimates that closely approximate those of the actual artery. This study is expected to be applicable in geometric reductions (and speed enhancements) for more complex patient-specific 3D simulations while maintaining accuracy.
title Effects of Geometric Modelling and Blood Rheology in Patient-Specific Arterial Blood Flow Simulations with Speed-Accuracy Trade-Off Analysis
topic Fluid Dynamics
url https://arxiv.org/abs/2503.23049