Enhancing Clinical Decision-Making: Integrating Multi-Agent Systems with Ethical AI Governance

Fuente: arXiv
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Autori principali: Chen, Ying-Jung, Albarqawi, Ahmad, Chen, Chi-Sheng
Natura: Preprint
Pubblicazione: 2025
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author Chen, Ying-Jung
Albarqawi, Ahmad
Chen, Chi-Sheng
author_facet Chen, Ying-Jung
Albarqawi, Ahmad
Chen, Chi-Sheng
contents Recent advances in the data-driven medicine approach, which integrates ethically managed and explainable artificial intelligence into clinical decision support systems (CDSS), are critical to ensure reliable and effective patient care. This paper focuses on comparing novel agent system designs that use modular agents to analyze laboratory results, vital signs, and clinical context, and to predict and validate results. We implement our agent system with the eICU database, including running lab analysis, vitals-only interpreters, and contextual reasoners agents first, then sharing the memory into the integration agent, prediction agent, transparency agent, and a validation agent. Our results suggest that the multi-agent system (MAS) performed better than the single-agent system (SAS) with mortality prediction accuracy (59\%, 56\%) and the mean error for length of stay (LOS)(4.37 days, 5.82 days), respectively. However, the transparency score for the SAS (86.21) is slightly better than the transparency score for MAS (85.5). Finally, this study suggests that our agent-based framework not only improves process transparency and prediction accuracy but also strengthens trustworthy AI-assisted decision support in an intensive care setting.
format Preprint
id arxiv_https___arxiv_org_abs_2504_03699
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing Clinical Decision-Making: Integrating Multi-Agent Systems with Ethical AI Governance
Chen, Ying-Jung
Albarqawi, Ahmad
Chen, Chi-Sheng
Artificial Intelligence
Computers and Society
Machine Learning
Multiagent Systems
Quantitative Methods
Recent advances in the data-driven medicine approach, which integrates ethically managed and explainable artificial intelligence into clinical decision support systems (CDSS), are critical to ensure reliable and effective patient care. This paper focuses on comparing novel agent system designs that use modular agents to analyze laboratory results, vital signs, and clinical context, and to predict and validate results. We implement our agent system with the eICU database, including running lab analysis, vitals-only interpreters, and contextual reasoners agents first, then sharing the memory into the integration agent, prediction agent, transparency agent, and a validation agent. Our results suggest that the multi-agent system (MAS) performed better than the single-agent system (SAS) with mortality prediction accuracy (59\%, 56\%) and the mean error for length of stay (LOS)(4.37 days, 5.82 days), respectively. However, the transparency score for the SAS (86.21) is slightly better than the transparency score for MAS (85.5). Finally, this study suggests that our agent-based framework not only improves process transparency and prediction accuracy but also strengthens trustworthy AI-assisted decision support in an intensive care setting.
title Enhancing Clinical Decision-Making: Integrating Multi-Agent Systems with Ethical AI Governance
topic Artificial Intelligence
Computers and Society
Machine Learning
Multiagent Systems
Quantitative Methods
url https://arxiv.org/abs/2504.03699