Plasma-Treated Polymeric Biomaterials for Improved Surface and Cell Adhesion

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Autori principali: Rondøn, Jairo, Gonzalez-Lizardo, Angel
Natura: Preprint
Pubblicazione: 2025
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author Rondøn, Jairo
Gonzalez-Lizardo, Angel
author_facet Rondøn, Jairo
Gonzalez-Lizardo, Angel
contents Surface modification of polymeric biomaterials using plasma has emerged as an effective strategy to optimize the cell-material interface without compromising the structural properties of the material. This work presents a critical review of the impact of low-temperature plasma treatment on enhancing cell adhesion, with emphasis on the physicochemical changes induced on the surface of polymers commonly used in biomedical applications. The mechanisms of interaction between reactive plasma species and the polymer surface are analyzed, along with techniques used to introduce hydrophilic functional groups that improve wettability and biocompatibility. Scientific evidence demonstrates that this type of surface modification promotes greater cell spreading, anchorage, and proliferation, making it particularly useful in the design of tissue engineering scaffolds, implantable devices, and vascular prostheses. Finally, current and future trends in the development of smart plasma-functionalized biomaterials are discussed, highlighting their role in regenerative medicine.
format Preprint
id arxiv_https___arxiv_org_abs_2504_03883
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Plasma-Treated Polymeric Biomaterials for Improved Surface and Cell Adhesion
Rondøn, Jairo
Gonzalez-Lizardo, Angel
Plasma Physics
Materials Science
Biological Physics
Surface modification of polymeric biomaterials using plasma has emerged as an effective strategy to optimize the cell-material interface without compromising the structural properties of the material. This work presents a critical review of the impact of low-temperature plasma treatment on enhancing cell adhesion, with emphasis on the physicochemical changes induced on the surface of polymers commonly used in biomedical applications. The mechanisms of interaction between reactive plasma species and the polymer surface are analyzed, along with techniques used to introduce hydrophilic functional groups that improve wettability and biocompatibility. Scientific evidence demonstrates that this type of surface modification promotes greater cell spreading, anchorage, and proliferation, making it particularly useful in the design of tissue engineering scaffolds, implantable devices, and vascular prostheses. Finally, current and future trends in the development of smart plasma-functionalized biomaterials are discussed, highlighting their role in regenerative medicine.
title Plasma-Treated Polymeric Biomaterials for Improved Surface and Cell Adhesion
topic Plasma Physics
Materials Science
Biological Physics
url https://arxiv.org/abs/2504.03883