Universal Lymph Node Detection in Multiparametric MRI with Selective Augmentation

Fuente: arXiv
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Autores principales: Mathai, Tejas Sudharshan, Lee, Sungwon, Shen, Thomas C., Lu, Zhiyong, Summers, Ronald M.
Formato: Preprint
Publicado: 2025
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author Mathai, Tejas Sudharshan
Lee, Sungwon
Shen, Thomas C.
Lu, Zhiyong
Summers, Ronald M.
author_facet Mathai, Tejas Sudharshan
Lee, Sungwon
Shen, Thomas C.
Lu, Zhiyong
Summers, Ronald M.
contents Robust localization of lymph nodes (LNs) in multiparametric MRI (mpMRI) is critical for the assessment of lymphadenopathy. Radiologists routinely measure the size of LN to distinguish benign from malignant nodes, which would require subsequent cancer staging. Sizing is a cumbersome task compounded by the diverse appearances of LNs in mpMRI, which renders their measurement difficult. Furthermore, smaller and potentially metastatic LNs could be missed during a busy clinical day. To alleviate these imaging and workflow problems, we propose a pipeline to universally detect both benign and metastatic nodes in the body for their ensuing measurement. The recently proposed VFNet neural network was employed to identify LN in T2 fat suppressed and diffusion weighted imaging (DWI) sequences acquired by various scanners with a variety of exam protocols. We also use a selective augmentation technique known as Intra-Label LISA (ILL) to diversify the input data samples the model sees during training, such that it improves its robustness during the evaluation phase. We achieved a sensitivity of $\sim$83\% with ILL vs. $\sim$80\% without ILL at 4 FP/vol. Compared with current LN detection approaches evaluated on mpMRI, we show a sensitivity improvement of $\sim$9\% at 4 FP/vol.
format Preprint
id arxiv_https___arxiv_org_abs_2504_05196
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Universal Lymph Node Detection in Multiparametric MRI with Selective Augmentation
Mathai, Tejas Sudharshan
Lee, Sungwon
Shen, Thomas C.
Lu, Zhiyong
Summers, Ronald M.
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Robust localization of lymph nodes (LNs) in multiparametric MRI (mpMRI) is critical for the assessment of lymphadenopathy. Radiologists routinely measure the size of LN to distinguish benign from malignant nodes, which would require subsequent cancer staging. Sizing is a cumbersome task compounded by the diverse appearances of LNs in mpMRI, which renders their measurement difficult. Furthermore, smaller and potentially metastatic LNs could be missed during a busy clinical day. To alleviate these imaging and workflow problems, we propose a pipeline to universally detect both benign and metastatic nodes in the body for their ensuing measurement. The recently proposed VFNet neural network was employed to identify LN in T2 fat suppressed and diffusion weighted imaging (DWI) sequences acquired by various scanners with a variety of exam protocols. We also use a selective augmentation technique known as Intra-Label LISA (ILL) to diversify the input data samples the model sees during training, such that it improves its robustness during the evaluation phase. We achieved a sensitivity of $\sim$83\% with ILL vs. $\sim$80\% without ILL at 4 FP/vol. Compared with current LN detection approaches evaluated on mpMRI, we show a sensitivity improvement of $\sim$9\% at 4 FP/vol.
title Universal Lymph Node Detection in Multiparametric MRI with Selective Augmentation
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2504.05196