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Bibliographic Details
Main Authors: Almanstötter, Marius, Vetter, Roman, Iber, Dagmar
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2504.05248
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author Almanstötter, Marius
Vetter, Roman
Iber, Dagmar
author_facet Almanstötter, Marius
Vetter, Roman
Iber, Dagmar
contents Parameter estimation for differential equations from measured data is an inverse problem prevalent across quantitative sciences. Physics-Informed Neural Networks (PINNs) have emerged as effective tools for solving such problems, especially with sparse measurements and incomplete system information. However, PINNs face convergence issues, stability problems, overfitting, and complex loss function design. Here we introduce PINNverse, a training paradigm that addresses these limitations by reformulating the learning process as a constrained differential optimization problem. This approach achieves a dynamic balance between data loss and differential equation residual loss during training while preventing overfitting. PINNverse combines the advantages of PINNs with the Modified Differential Method of Multipliers to enable convergence on any point on the Pareto front. We demonstrate robust and accurate parameter estimation from noisy data in four classical ODE and PDE models from physics and biology. Our method enables accurate parameter inference also when the forward problem is expensive to solve.
format Preprint
id arxiv_https___arxiv_org_abs_2504_05248
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle PINNverse: Accurate parameter estimation in differential equations from noisy data with constrained physics-informed neural networks
Almanstötter, Marius
Vetter, Roman
Iber, Dagmar
Machine Learning
Artificial Intelligence
Computational Physics
Parameter estimation for differential equations from measured data is an inverse problem prevalent across quantitative sciences. Physics-Informed Neural Networks (PINNs) have emerged as effective tools for solving such problems, especially with sparse measurements and incomplete system information. However, PINNs face convergence issues, stability problems, overfitting, and complex loss function design. Here we introduce PINNverse, a training paradigm that addresses these limitations by reformulating the learning process as a constrained differential optimization problem. This approach achieves a dynamic balance between data loss and differential equation residual loss during training while preventing overfitting. PINNverse combines the advantages of PINNs with the Modified Differential Method of Multipliers to enable convergence on any point on the Pareto front. We demonstrate robust and accurate parameter estimation from noisy data in four classical ODE and PDE models from physics and biology. Our method enables accurate parameter inference also when the forward problem is expensive to solve.
title PINNverse: Accurate parameter estimation in differential equations from noisy data with constrained physics-informed neural networks
topic Machine Learning
Artificial Intelligence
Computational Physics
url https://arxiv.org/abs/2504.05248