Endoscopic fiber-coupled diamond magnetometer for cancer surgery

Fuente: arXiv
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Main Authors: Newman, A. J., Graham, S. M., Stephen, C. J., Edmonds, A. M., Markham, M. L., Morley, G. W.
Format: Preprint
Published: 2025
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author Newman, A. J.
Graham, S. M.
Stephen, C. J.
Edmonds, A. M.
Markham, M. L.
Morley, G. W.
author_facet Newman, A. J.
Graham, S. M.
Stephen, C. J.
Edmonds, A. M.
Markham, M. L.
Morley, G. W.
contents Interoperative measurements using magnetic sensors is a valuable technique in cancer surgery for finding magnetic tracers. Here we present a fiber-coupled nitrogen-vacancy (N-V) center magnetometer capable of detecting iron oxide suspension (MagTrace from Endomagnetics Ltd.) used in breast cancer surgeries. Detection of an iron mass as low as 0.56~mg has been demonstrated, 100 times less than that of a recommended dose at a maximum distance of 5.8~mm. Detection of an iron concentration as low as 2.8 mg/ml has also been demonstrated, 20 times less than a recommended dose. The maximum working distance from the sensor can be as large as 14.6~mm for higher concentrations. The sensor head has a maximum diameter of 10~mm which would allow it to be used for endoscopy, laparoscopy and interoperative surgery.
format Preprint
id arxiv_https___arxiv_org_abs_2504_05884
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Endoscopic fiber-coupled diamond magnetometer for cancer surgery
Newman, A. J.
Graham, S. M.
Stephen, C. J.
Edmonds, A. M.
Markham, M. L.
Morley, G. W.
Medical Physics
Materials Science
Quantum Physics
Interoperative measurements using magnetic sensors is a valuable technique in cancer surgery for finding magnetic tracers. Here we present a fiber-coupled nitrogen-vacancy (N-V) center magnetometer capable of detecting iron oxide suspension (MagTrace from Endomagnetics Ltd.) used in breast cancer surgeries. Detection of an iron mass as low as 0.56~mg has been demonstrated, 100 times less than that of a recommended dose at a maximum distance of 5.8~mm. Detection of an iron concentration as low as 2.8 mg/ml has also been demonstrated, 20 times less than a recommended dose. The maximum working distance from the sensor can be as large as 14.6~mm for higher concentrations. The sensor head has a maximum diameter of 10~mm which would allow it to be used for endoscopy, laparoscopy and interoperative surgery.
title Endoscopic fiber-coupled diamond magnetometer for cancer surgery
topic Medical Physics
Materials Science
Quantum Physics
url https://arxiv.org/abs/2504.05884