Zeus: Zero-shot LLM Instruction for Union Segmentation in Multimodal Medical Imaging

Fuente: arXiv
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Hauptverfasser: Dai, Siyuan, Ye, Kai, Liu, Guodong, Tang, Haoteng, Zhan, Liang
Format: Preprint
Veröffentlicht: 2025
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author Dai, Siyuan
Ye, Kai
Liu, Guodong
Tang, Haoteng
Zhan, Liang
author_facet Dai, Siyuan
Ye, Kai
Liu, Guodong
Tang, Haoteng
Zhan, Liang
contents Medical image segmentation has achieved remarkable success through the continuous advancement of UNet-based and Transformer-based foundation backbones. However, clinical diagnosis in the real world often requires integrating domain knowledge, especially textual information. Conducting multimodal learning involves visual and text modalities shown as a solution, but collecting paired vision-language datasets is expensive and time-consuming, posing significant challenges. Inspired by the superior ability in numerous cross-modal tasks for Large Language Models (LLMs), we proposed a novel Vision-LLM union framework to address the issues. Specifically, we introduce frozen LLMs for zero-shot instruction generation based on corresponding medical images, imitating the radiology scanning and report generation process. {To better approximate real-world diagnostic processes}, we generate more precise text instruction from multimodal radiology images (e.g., T1-w or T2-w MRI and CT). Based on the impressive ability of semantic understanding and rich knowledge of LLMs. This process emphasizes extracting special features from different modalities and reunion the information for the ultimate clinical diagnostic. With generated text instruction, our proposed union segmentation framework can handle multimodal segmentation without prior collected vision-language datasets. To evaluate our proposed method, we conduct comprehensive experiments with influential baselines, the statistical results and the visualized case study demonstrate the superiority of our novel method.}
format Preprint
id arxiv_https___arxiv_org_abs_2504_07336
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Zeus: Zero-shot LLM Instruction for Union Segmentation in Multimodal Medical Imaging
Dai, Siyuan
Ye, Kai
Liu, Guodong
Tang, Haoteng
Zhan, Liang
Computer Vision and Pattern Recognition
Artificial Intelligence
Medical image segmentation has achieved remarkable success through the continuous advancement of UNet-based and Transformer-based foundation backbones. However, clinical diagnosis in the real world often requires integrating domain knowledge, especially textual information. Conducting multimodal learning involves visual and text modalities shown as a solution, but collecting paired vision-language datasets is expensive and time-consuming, posing significant challenges. Inspired by the superior ability in numerous cross-modal tasks for Large Language Models (LLMs), we proposed a novel Vision-LLM union framework to address the issues. Specifically, we introduce frozen LLMs for zero-shot instruction generation based on corresponding medical images, imitating the radiology scanning and report generation process. {To better approximate real-world diagnostic processes}, we generate more precise text instruction from multimodal radiology images (e.g., T1-w or T2-w MRI and CT). Based on the impressive ability of semantic understanding and rich knowledge of LLMs. This process emphasizes extracting special features from different modalities and reunion the information for the ultimate clinical diagnostic. With generated text instruction, our proposed union segmentation framework can handle multimodal segmentation without prior collected vision-language datasets. To evaluate our proposed method, we conduct comprehensive experiments with influential baselines, the statistical results and the visualized case study demonstrate the superiority of our novel method.}
title Zeus: Zero-shot LLM Instruction for Union Segmentation in Multimodal Medical Imaging
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2504.07336