Cover Image

Representation Meets Optimization: Training PINNs and PIKANs for Gray-Box Discovery in Systems Pharmacology

Fuente: arXiv

Saved in:

Bibliographic Details
Main Authors:	Daryakenari, Nazanin Ahmadi, Shukla, Khemraj, Karniadakis, George Em
Format:	Preprint
Published:	2025
Subjects:	Quantitative Methods Artificial Intelligence 35R30 (Primary), 65M32, 92C50 (Secondary) I.2.6; G.1.7; G.1.10
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Exploring Multi-Objective Trade-offs in Reference Compound Selection for Validation Studies of Toxicity Assays
by: Ohto, Yohei, et al.
Published: (2025)

Estimating the tails of the spectrum of the Hessian of the log-likelihood for \textit{ab-initio} single-particle reconstruction in electron cryomicroscopy
by: Rangan, Aaditya V., et al.
Published: (2024)

Time to revisit the endpoint dilution assay and to replace TCID$_{50}$ and PFU as measures of a virus sample's infection concentration
by: Cresta, Daniel, et al.
Published: (2021)

Physics-Informed Deep Inverse Operator Networks for Solving PDE Inverse Problems
by: Cho, Sung Woong, et al.
Published: (2024)

An integrated heart-torso electromechanical model for the simulation of electrophysiogical outputs accounting for myocardial deformation
by: Zappon, Elena, et al.
Published: (2024)

Learning Hamiltonian flows from numerical integrators and examples
by: Fang, Rui, et al.
Published: (2025)

Expected and minimal values of a universal tree balance index
by: Manojlović, Veselin, et al.
Published: (2025)

GridapROMs.jl: Efficient reduced order modelling in the Julia programming language
by: Mueller, Nicholas, et al.
Published: (2025)

A non-standard numerical scheme for an age-of-infection epidemic model
by: Messina, Eleonora, et al.
Published: (2021)

CMINNs: Compartment Model Informed Neural Networks -- Unlocking Drug Dynamics
by: Daryakenari, Nazanin Ahmadi, et al.
Published: (2024)

An Evaluation of the Pedagogical Soundness and Usability of AI-Generated Lesson Plans Across Different Models and Prompt Frameworks in High-School Physics
by: Liu, Xincheng
Published: (2025)

An efficient end-to-end computational framework for the generation of ECG calibrated volumetric models of human atrial electrophysiology
by: Zappon, Elena, et al.
Published: (2025)

Experimental and numerical analysis of a full-scale timber-concrete-composite beam from simply supported to frame-connected
by: Otero-Chans, Dolores, et al.
Published: (2025)

Numerical Performance of the Implicitly Restarted Arnoldi Method in OFP8, Bfloat16, Posit, and Takum Arithmetics
by: Hunhold, Laslo, et al.
Published: (2025)

Evaluation of Bfloat16, Posit, and Takum Arithmetics in Sparse Linear Solvers
by: Hunhold, Laslo, et al.
Published: (2024)

Spectral Methods via FFTs in Emerging Machine Number Formats: OFP8, Bfloat16, Posit, and Takum Arithmetics
by: Hunhold, Laslo, et al.
Published: (2025)

Covariance Matrix Analysis for Optimal Portfolio Selection
by: Keith, Lim Hao Shen
Published: (2024)

Pricing and Hedging Strategies for Cross-Currency Equity Protection Swaps
by: Rutkowski, Marek, et al.
Published: (2024)

Inhomogeneous graph trend filtering via a l2,0 cardinality penalty
by: Huang, Xiaoqing, et al.
Published: (2023)

The Unfitted Discontinuous Galerkin Method for Solving the EEG Forward Problem
by: Nüßing, Andreas, et al.
Published: (2016)

Augmenting MRI scan data with real-time predictions of glioblastoma brain tumor evolution using faster exponential time integrators
by: Pabisz, Magdalena, et al.
Published: (2024)

Density Estimation via Measure Transport: Outlook for Applications in the Biological Sciences
by: Lopez-Marrero, Vanessa, et al.
Published: (2023)

Assembly line balancing considering stochastic task times and production defects
by: Nur, Gazi Nazia, et al.
Published: (2025)

Learning a robust shape parameter for RBF approximation
by: Veiga, Maria Han, et al.
Published: (2024)

Theoretical Framework for Tempered Fractional Gradient Descent: Application to Breast Cancer Classification
by: Naifar, Omar
Published: (2025)

A convergence framework for energy minimisation of linear self-adjoint elliptic PDEs in nonlinear approximation spaces
by: Magueresse, Alexandre, et al.
Published: (2025)

Energy minimisation using overlapping tensor-product free-knot B-splines
by: Magueresse, Alexandre, et al.
Published: (2025)

A Reanalysis of the FDA's Benefit--Risk Assessment of Moderna's mRNA-1273 COVID Vaccine Based on a Model Incorporating Benefits Derived from Prior COVID Infection
by: Bourdon, Paul S., et al.
Published: (2024)

Optimizing growth performance of Abelmoschus esculentus (L.) via synergistic effects of biogenic Cu/Ni/Co oxide nanoparticles in conjunction with rice straw and pressmud based vermicompost
by: Yadav, Shalu, et al.
Published: (2024)

Enhancing mortality prediction in cardiac arrest ICU patients through meta-modeling of structured clinical data from MIMIC-IV
by: Mamatov, Nursultan, et al.
Published: (2025)

Layer Probing Improves Kinase Functional Prediction with Protein Language Models
by: Kumar, Ajit, et al.
Published: (2025)

Renal function changes in chronic hepatitis B patients
by: Zhao, Jinhua, et al.
Published: (2024)

A new approach to data assimilation initialization problems with sparse data using multiple cost functions
by: Abers, David J., et al.
Published: (2024)

Mathematical Modeling of Biofilm Eradication Using Optimal Control
by: Akber, Rehan, et al.
Published: (2025)

Towards Coordinate- and Dimension-Agnostic Machine Learning for Partial Differential Equations
by: Phan, Trung V., et al.
Published: (2025)

From PINNs to PIKANs: Recent Advances in Physics-Informed Machine Learning
by: Toscano, Juan Diego, et al.
Published: (2024)

A multiphase cubic MARS method for fourth- and higher-order interface tracking of two or more materials with arbitrary topology and geometry
by: Tan, Yan, et al.
Published: (2025)

Causal Portfolio Optimization: Principles and Sensitivity-Based Solutions
by: Dominguez, Alejandro Rodriguez
Published: (2025)

Causal PDE-Control Models for Dynamic Portfolio Optimization with Latent Drivers
by: Dominguez, Alejandro Rodriguez
Published: (2025)

Exploring Prime Number Classification: Achieving High Recall Rate and Rapid Convergence with Sparse Encoding
by: Lee, Serin, et al.
Published: (2024)