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Main Authors: Rodrigues, R., Galindo-Rosales, F. J., Campo-Deaño, L.
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2504.09194
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author Rodrigues, R.
Galindo-Rosales, F. J.
Campo-Deaño, L.
author_facet Rodrigues, R.
Galindo-Rosales, F. J.
Campo-Deaño, L.
contents Magnetic particle under external fields can be useful in various medical applications, gaining access to the whole body if deployed in the bloodstream. Localised drug delivery, haemorrhage control, and cancer treatment are among the applications that have the potential to become revolutionary therapies. Despite this interest, a magnetorheological characterisation of particle-seeded blood has yet to be achieved. In this work, we evaluate the magnetorheological response of blood analogues seeded with paramagnetic particles in different concentrations, under the effects of a uniform, density-varying magnetic field. Through steady shear experiments, we encounter the usual magnetically-induced shear thinning response, and oscillatory shear results point toward significant alterations in the fluids' microstructure. However, experimental limitations make it difficult to accurately evaluate the oscillatory shear response of such rheologically subtle fluids, limiting both the quality and quantity of achievable information. Despite experimental limitations, our results demonstrate that magnetic fields can induce marked and quantifiable rheological changes in seeded blood analogues. The framework established here provides a foundation for future studies on real blood samples and for the design of magnetically responsive biomedical systems.
format Preprint
id arxiv_https___arxiv_org_abs_2504_09194
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Magnetorheological Characterization of Blood Analogues Seeded with Paramagnetic Particles
Rodrigues, R.
Galindo-Rosales, F. J.
Campo-Deaño, L.
Fluid Dynamics
Magnetic particle under external fields can be useful in various medical applications, gaining access to the whole body if deployed in the bloodstream. Localised drug delivery, haemorrhage control, and cancer treatment are among the applications that have the potential to become revolutionary therapies. Despite this interest, a magnetorheological characterisation of particle-seeded blood has yet to be achieved. In this work, we evaluate the magnetorheological response of blood analogues seeded with paramagnetic particles in different concentrations, under the effects of a uniform, density-varying magnetic field. Through steady shear experiments, we encounter the usual magnetically-induced shear thinning response, and oscillatory shear results point toward significant alterations in the fluids' microstructure. However, experimental limitations make it difficult to accurately evaluate the oscillatory shear response of such rheologically subtle fluids, limiting both the quality and quantity of achievable information. Despite experimental limitations, our results demonstrate that magnetic fields can induce marked and quantifiable rheological changes in seeded blood analogues. The framework established here provides a foundation for future studies on real blood samples and for the design of magnetically responsive biomedical systems.
title Magnetorheological Characterization of Blood Analogues Seeded with Paramagnetic Particles
topic Fluid Dynamics
url https://arxiv.org/abs/2504.09194