Mixture-of-Shape-Experts (MoSE): End-to-End Shape Dictionary Framework to Prompt SAM for Generalizable Medical Segmentation

Fuente: arXiv
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Autori principali: Wei, Jia, Zhao, Xiaoqi, Woo, Jonghye, Ouyang, Jinsong, Fakhri, Georges El, Chen, Qingyu, Liu, Xiaofeng
Natura: Preprint
Pubblicazione: 2025
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author Wei, Jia
Zhao, Xiaoqi
Woo, Jonghye
Ouyang, Jinsong
Fakhri, Georges El
Chen, Qingyu
Liu, Xiaofeng
author_facet Wei, Jia
Zhao, Xiaoqi
Woo, Jonghye
Ouyang, Jinsong
Fakhri, Georges El
Chen, Qingyu
Liu, Xiaofeng
contents Single domain generalization (SDG) has recently attracted growing attention in medical image segmentation. One promising strategy for SDG is to leverage consistent semantic shape priors across different imaging protocols, scanner vendors, and clinical sites. However, existing dictionary learning methods that encode shape priors often suffer from limited representational power with a small set of offline computed shape elements, or overfitting when the dictionary size grows. Moreover, they are not readily compatible with large foundation models such as the Segment Anything Model (SAM). In this paper, we propose a novel Mixture-of-Shape-Experts (MoSE) framework that seamlessly integrates the idea of mixture-of-experts (MoE) training into dictionary learning to efficiently capture diverse and robust shape priors. Our method conceptualizes each dictionary atom as a shape expert, which specializes in encoding distinct semantic shape information. A gating network dynamically fuses these shape experts into a robust shape map, with sparse activation guided by SAM encoding to prevent overfitting. We further provide this shape map as a prompt to SAM, utilizing the powerful generalization capability of SAM through bidirectional integration. All modules, including the shape dictionary, are trained in an end-to-end manner. Extensive experiments on multiple public datasets demonstrate its effectiveness.
format Preprint
id arxiv_https___arxiv_org_abs_2504_09601
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Mixture-of-Shape-Experts (MoSE): End-to-End Shape Dictionary Framework to Prompt SAM for Generalizable Medical Segmentation
Wei, Jia
Zhao, Xiaoqi
Woo, Jonghye
Ouyang, Jinsong
Fakhri, Georges El
Chen, Qingyu
Liu, Xiaofeng
Computer Vision and Pattern Recognition
Machine Learning
Multimedia
Image and Video Processing
Medical Physics
Single domain generalization (SDG) has recently attracted growing attention in medical image segmentation. One promising strategy for SDG is to leverage consistent semantic shape priors across different imaging protocols, scanner vendors, and clinical sites. However, existing dictionary learning methods that encode shape priors often suffer from limited representational power with a small set of offline computed shape elements, or overfitting when the dictionary size grows. Moreover, they are not readily compatible with large foundation models such as the Segment Anything Model (SAM). In this paper, we propose a novel Mixture-of-Shape-Experts (MoSE) framework that seamlessly integrates the idea of mixture-of-experts (MoE) training into dictionary learning to efficiently capture diverse and robust shape priors. Our method conceptualizes each dictionary atom as a shape expert, which specializes in encoding distinct semantic shape information. A gating network dynamically fuses these shape experts into a robust shape map, with sparse activation guided by SAM encoding to prevent overfitting. We further provide this shape map as a prompt to SAM, utilizing the powerful generalization capability of SAM through bidirectional integration. All modules, including the shape dictionary, are trained in an end-to-end manner. Extensive experiments on multiple public datasets demonstrate its effectiveness.
title Mixture-of-Shape-Experts (MoSE): End-to-End Shape Dictionary Framework to Prompt SAM for Generalizable Medical Segmentation
topic Computer Vision and Pattern Recognition
Machine Learning
Multimedia
Image and Video Processing
Medical Physics
url https://arxiv.org/abs/2504.09601