Modeling liquid-mediated interactions for close-to-substrate magnetic microparticle transport in dynamic magnetic field landscapes
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arXiv
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| Main Authors: | , , , , , |
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| Format: | Preprint |
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2025
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| _version_ | 1866913911045881856 |
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| author | Gusenbauer, Markus Huhnstock, Rico Kovacs, Alexander Oezelt, Harald Ehresmann, Arno Schrefl, Thomas |
| author_facet | Gusenbauer, Markus Huhnstock, Rico Kovacs, Alexander Oezelt, Harald Ehresmann, Arno Schrefl, Thomas |
| contents | Understanding the on-chip motion of magnetic particles in a microfluidic environment is key to realizing magnetic particle-based Lab-on-a-chip systems for medical diagnostics. In this work, a simulation model is established to quantify the trajectory of a single particle moving close to a polymer surface in a quiescent liquid. The simulations include hydrodynamic, magnetostatic, and Derjaguin-Landau-Verwey-Overbeek (DLVO) interactions. They are applied to particle motion driven by a dynamically changing magnetic field landscape created by engineered parallel-stripe magnetic domains superposed by a homogeneous, time-varying external magnetic field. The simulation model is adapted to experiments in terms of fluid-particle interactions with the magnetic field landscape approximated by analytic equations under the assumption of surface charges. Varying simulation parameters, we especially clarify the impact of liquid-mediated DLVO interactions, which are essential for diagnostic applications, on the 3D trajectory of the particle. A comparison to experimental results validates our simulation approach. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2504_10963 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Modeling liquid-mediated interactions for close-to-substrate magnetic microparticle transport in dynamic magnetic field landscapes Gusenbauer, Markus Huhnstock, Rico Kovacs, Alexander Oezelt, Harald Ehresmann, Arno Schrefl, Thomas Fluid Dynamics Applied Physics Computational Physics Understanding the on-chip motion of magnetic particles in a microfluidic environment is key to realizing magnetic particle-based Lab-on-a-chip systems for medical diagnostics. In this work, a simulation model is established to quantify the trajectory of a single particle moving close to a polymer surface in a quiescent liquid. The simulations include hydrodynamic, magnetostatic, and Derjaguin-Landau-Verwey-Overbeek (DLVO) interactions. They are applied to particle motion driven by a dynamically changing magnetic field landscape created by engineered parallel-stripe magnetic domains superposed by a homogeneous, time-varying external magnetic field. The simulation model is adapted to experiments in terms of fluid-particle interactions with the magnetic field landscape approximated by analytic equations under the assumption of surface charges. Varying simulation parameters, we especially clarify the impact of liquid-mediated DLVO interactions, which are essential for diagnostic applications, on the 3D trajectory of the particle. A comparison to experimental results validates our simulation approach. |
| title | Modeling liquid-mediated interactions for close-to-substrate magnetic microparticle transport in dynamic magnetic field landscapes |
| topic | Fluid Dynamics Applied Physics Computational Physics |
| url | https://arxiv.org/abs/2504.10963 |