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Main Authors: Hamrani, Abderrachid, Leizaola, Daniela, Sousa, Renato, Ponce, Jose P., Mathis, Stanley, Armstrong, David G., Godavarty, Anuradha
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2504.17628
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author Hamrani, Abderrachid
Leizaola, Daniela
Sousa, Renato
Ponce, Jose P.
Mathis, Stanley
Armstrong, David G.
Godavarty, Anuradha
author_facet Hamrani, Abderrachid
Leizaola, Daniela
Sousa, Renato
Ponce, Jose P.
Mathis, Stanley
Armstrong, David G.
Godavarty, Anuradha
contents Diabetic foot ulcers (DFUs) pose a significant challenge in healthcare, requiring precise and efficient wound assessment to enhance patient outcomes. This study introduces the Attention Diffusion Zero-shot Unsupervised System (ADZUS), a novel text-guided diffusion model that performs wound segmentation without relying on labeled training data. Unlike conventional deep learning models, which require extensive annotation, ADZUS leverages zero-shot learning to dynamically adapt segmentation based on descriptive prompts, offering enhanced flexibility and adaptability in clinical applications. Experimental evaluations demonstrate that ADZUS surpasses traditional and state-of-the-art segmentation models, achieving an IoU of 86.68\% and the highest precision of 94.69\% on the chronic wound dataset, outperforming supervised approaches such as FUSegNet. Further validation on a custom-curated DFU dataset reinforces its robustness, with ADZUS achieving a median DSC of 75\%, significantly surpassing FUSegNet's 45\%. The model's text-guided segmentation capability enables real-time customization of segmentation outputs, allowing targeted analysis of wound characteristics based on clinical descriptions. Despite its competitive performance, the computational cost of diffusion-based inference and the need for potential fine-tuning remain areas for future improvement. ADZUS represents a transformative step in wound segmentation, providing a scalable, efficient, and adaptable AI-driven solution for medical imaging.
format Preprint
id arxiv_https___arxiv_org_abs_2504_17628
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Beyond Labels: Zero-Shot Diabetic Foot Ulcer Wound Segmentation with Self-attention Diffusion Models and the Potential for Text-Guided Customization
Hamrani, Abderrachid
Leizaola, Daniela
Sousa, Renato
Ponce, Jose P.
Mathis, Stanley
Armstrong, David G.
Godavarty, Anuradha
Image and Video Processing
Computer Vision and Pattern Recognition
Diabetic foot ulcers (DFUs) pose a significant challenge in healthcare, requiring precise and efficient wound assessment to enhance patient outcomes. This study introduces the Attention Diffusion Zero-shot Unsupervised System (ADZUS), a novel text-guided diffusion model that performs wound segmentation without relying on labeled training data. Unlike conventional deep learning models, which require extensive annotation, ADZUS leverages zero-shot learning to dynamically adapt segmentation based on descriptive prompts, offering enhanced flexibility and adaptability in clinical applications. Experimental evaluations demonstrate that ADZUS surpasses traditional and state-of-the-art segmentation models, achieving an IoU of 86.68\% and the highest precision of 94.69\% on the chronic wound dataset, outperforming supervised approaches such as FUSegNet. Further validation on a custom-curated DFU dataset reinforces its robustness, with ADZUS achieving a median DSC of 75\%, significantly surpassing FUSegNet's 45\%. The model's text-guided segmentation capability enables real-time customization of segmentation outputs, allowing targeted analysis of wound characteristics based on clinical descriptions. Despite its competitive performance, the computational cost of diffusion-based inference and the need for potential fine-tuning remain areas for future improvement. ADZUS represents a transformative step in wound segmentation, providing a scalable, efficient, and adaptable AI-driven solution for medical imaging.
title Beyond Labels: Zero-Shot Diabetic Foot Ulcer Wound Segmentation with Self-attention Diffusion Models and the Potential for Text-Guided Customization
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2504.17628