Towards a HIPAA Compliant Agentic AI System in Healthcare

Fuente: arXiv
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Main Authors: Neupane, Subash, Mittal, Sudip, Rahimi, Shahram
Format: Preprint
Published: 2025
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author Neupane, Subash
Mittal, Sudip
Rahimi, Shahram
author_facet Neupane, Subash
Mittal, Sudip
Rahimi, Shahram
contents Agentic AI systems powered by Large Language Models (LLMs) as their foundational reasoning engine, are transforming clinical workflows such as medical report generation and clinical summarization by autonomously analyzing sensitive healthcare data and executing decisions with minimal human oversight. However, their adoption demands strict compliance with regulatory frameworks such as Health Insurance Portability and Accountability Act (HIPAA), particularly when handling Protected Health Information (PHI). This work-in-progress paper introduces a HIPAA-compliant Agentic AI framework that enforces regulatory compliance through dynamic, context-aware policy enforcement. Our framework integrates three core mechanisms: (1) Attribute-Based Access Control (ABAC) for granular PHI governance, (2) a hybrid PHI sanitization pipeline combining regex patterns and BERT-based model to minimize leakage, and (3) immutable audit trails for compliance verification.
format Preprint
id arxiv_https___arxiv_org_abs_2504_17669
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Towards a HIPAA Compliant Agentic AI System in Healthcare
Neupane, Subash
Mittal, Sudip
Rahimi, Shahram
Multiagent Systems
Artificial Intelligence
Emerging Technologies
Agentic AI systems powered by Large Language Models (LLMs) as their foundational reasoning engine, are transforming clinical workflows such as medical report generation and clinical summarization by autonomously analyzing sensitive healthcare data and executing decisions with minimal human oversight. However, their adoption demands strict compliance with regulatory frameworks such as Health Insurance Portability and Accountability Act (HIPAA), particularly when handling Protected Health Information (PHI). This work-in-progress paper introduces a HIPAA-compliant Agentic AI framework that enforces regulatory compliance through dynamic, context-aware policy enforcement. Our framework integrates three core mechanisms: (1) Attribute-Based Access Control (ABAC) for granular PHI governance, (2) a hybrid PHI sanitization pipeline combining regex patterns and BERT-based model to minimize leakage, and (3) immutable audit trails for compliance verification.
title Towards a HIPAA Compliant Agentic AI System in Healthcare
topic Multiagent Systems
Artificial Intelligence
Emerging Technologies
url https://arxiv.org/abs/2504.17669