Low-Rank Adaptive Structural Priors for Generalizable Diabetic Retinopathy Grading

Fuente: arXiv
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Auteurs principaux: Wang, Yunxuan, Yin, Ray, Tan, Yumei, Chen, Hao, Xia, Haiying
Format: Preprint
Publié: 2025
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author Wang, Yunxuan
Yin, Ray
Tan, Yumei
Chen, Hao
Xia, Haiying
author_facet Wang, Yunxuan
Yin, Ray
Tan, Yumei
Chen, Hao
Xia, Haiying
contents Diabetic retinopathy (DR), a serious ocular complication of diabetes, is one of the primary causes of vision loss among retinal vascular diseases. Deep learning methods have been extensively applied in the grading of diabetic retinopathy (DR). However, their performance declines significantly when applied to data outside the training distribution due to domain shifts. Domain generalization (DG) has emerged as a solution to this challenge. However, most existing DG methods overlook lesion-specific features, resulting in insufficient accuracy. In this paper, we propose a novel approach that enhances existing DG methods by incorporating structural priors, inspired by the observation that DR grading is heavily dependent on vessel and lesion structures. We introduce Low-rank Adaptive Structural Priors (LoASP), a plug-and-play framework designed for seamless integration with existing DG models. LoASP improves generalization by learning adaptive structural representations that are finely tuned to the complexities of DR diagnosis. Extensive experiments on eight diverse datasets validate its effectiveness in both single-source and multi-source domain scenarios. Furthermore, visualizations reveal that the learned structural priors intuitively align with the intricate architecture of the vessels and lesions, providing compelling insights into their interpretability and diagnostic relevance.
format Preprint
id arxiv_https___arxiv_org_abs_2504_19362
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Low-Rank Adaptive Structural Priors for Generalizable Diabetic Retinopathy Grading
Wang, Yunxuan
Yin, Ray
Tan, Yumei
Chen, Hao
Xia, Haiying
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Diabetic retinopathy (DR), a serious ocular complication of diabetes, is one of the primary causes of vision loss among retinal vascular diseases. Deep learning methods have been extensively applied in the grading of diabetic retinopathy (DR). However, their performance declines significantly when applied to data outside the training distribution due to domain shifts. Domain generalization (DG) has emerged as a solution to this challenge. However, most existing DG methods overlook lesion-specific features, resulting in insufficient accuracy. In this paper, we propose a novel approach that enhances existing DG methods by incorporating structural priors, inspired by the observation that DR grading is heavily dependent on vessel and lesion structures. We introduce Low-rank Adaptive Structural Priors (LoASP), a plug-and-play framework designed for seamless integration with existing DG models. LoASP improves generalization by learning adaptive structural representations that are finely tuned to the complexities of DR diagnosis. Extensive experiments on eight diverse datasets validate its effectiveness in both single-source and multi-source domain scenarios. Furthermore, visualizations reveal that the learned structural priors intuitively align with the intricate architecture of the vessels and lesions, providing compelling insights into their interpretability and diagnostic relevance.
title Low-Rank Adaptive Structural Priors for Generalizable Diabetic Retinopathy Grading
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2504.19362