Advances in Approximate Bayesian Inference for Models in Epidemiology

Fuente: arXiv
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Autores principales: Li, Xiahui, Chadwick, Fergus, Swallow, Ben
Formato: Preprint
Publicado: 2025
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author Li, Xiahui
Chadwick, Fergus
Swallow, Ben
author_facet Li, Xiahui
Chadwick, Fergus
Swallow, Ben
contents Bayesian inference methods are useful in infectious diseases modeling due to their capability to propagate uncertainty, manage sparse data, incorporate latent structures, and address high-dimensional parameter spaces. However, parameter inference through assimilation of observational data in these models remains challenging. While asymptotically exact Bayesian methods offer theoretical guarantees for accurate inference, they can be computationally demanding and impractical for real-time outbreak analysis. This review synthesizes recent advances in approximate Bayesian inference methods that aim to balance inferential accuracy with scalability. We focus on four prominent families: Approximate Bayesian Computation, Bayesian Synthetic Likelihood, Integrated Nested Laplace Approximation, and Variational Inference. For each method, we evaluate its relevance to epidemiological applications, emphasizing innovations that improve both computational efficiency and inference accuracy. We also offer practical guidance on method selection across a range of modeling scenarios. Finally, we identify hybrid exact approximate inference as a promising frontier that combines methodological rigor with the scalability needed for the response to outbreaks. This review provides epidemiologists with a conceptual framework to navigate the trade-off between statistical accuracy and computational feasibility in contemporary disease modeling.
format Preprint
id arxiv_https___arxiv_org_abs_2504_19698
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Advances in Approximate Bayesian Inference for Models in Epidemiology
Li, Xiahui
Chadwick, Fergus
Swallow, Ben
Methodology
Computation
Bayesian inference methods are useful in infectious diseases modeling due to their capability to propagate uncertainty, manage sparse data, incorporate latent structures, and address high-dimensional parameter spaces. However, parameter inference through assimilation of observational data in these models remains challenging. While asymptotically exact Bayesian methods offer theoretical guarantees for accurate inference, they can be computationally demanding and impractical for real-time outbreak analysis. This review synthesizes recent advances in approximate Bayesian inference methods that aim to balance inferential accuracy with scalability. We focus on four prominent families: Approximate Bayesian Computation, Bayesian Synthetic Likelihood, Integrated Nested Laplace Approximation, and Variational Inference. For each method, we evaluate its relevance to epidemiological applications, emphasizing innovations that improve both computational efficiency and inference accuracy. We also offer practical guidance on method selection across a range of modeling scenarios. Finally, we identify hybrid exact approximate inference as a promising frontier that combines methodological rigor with the scalability needed for the response to outbreaks. This review provides epidemiologists with a conceptual framework to navigate the trade-off between statistical accuracy and computational feasibility in contemporary disease modeling.
title Advances in Approximate Bayesian Inference for Models in Epidemiology
topic Methodology
Computation
url https://arxiv.org/abs/2504.19698