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Hauptverfasser: Magnus, Joshua H., Nguyen, Lam T., Alevy, Elana G., Sawyer, Travis W., Crossley, Samuel D., Kieu, Khanh
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2504.20309
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author Magnus, Joshua H.
Nguyen, Lam T.
Alevy, Elana G.
Sawyer, Travis W.
Crossley, Samuel D.
Kieu, Khanh
author_facet Magnus, Joshua H.
Nguyen, Lam T.
Alevy, Elana G.
Sawyer, Travis W.
Crossley, Samuel D.
Kieu, Khanh
contents We report the application of fifth order nonlinear optical processes for multiphoton microscopy, including fifth harmonic and 5-photon excitation fluorescence. This novel imaging modality has been characterized with spectral and power dependence measurements. The advantages of fifth harmonic and 5-photon excitation fluorescence imaging are higher resolution and use of longer wavelength excitation sources, which may allow deeper penetration depth, while still exciting near-UV to blue fluorophores. This imaging modality may find interesting applications in biological research, materials characterization, geologic studies, and semiconductor manufacturing.
format Preprint
id arxiv_https___arxiv_org_abs_2504_20309
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Fifth Harmonic and Five-Photon Excitation Fluorescence Multiphoton Microscopy
Magnus, Joshua H.
Nguyen, Lam T.
Alevy, Elana G.
Sawyer, Travis W.
Crossley, Samuel D.
Kieu, Khanh
Optics
We report the application of fifth order nonlinear optical processes for multiphoton microscopy, including fifth harmonic and 5-photon excitation fluorescence. This novel imaging modality has been characterized with spectral and power dependence measurements. The advantages of fifth harmonic and 5-photon excitation fluorescence imaging are higher resolution and use of longer wavelength excitation sources, which may allow deeper penetration depth, while still exciting near-UV to blue fluorophores. This imaging modality may find interesting applications in biological research, materials characterization, geologic studies, and semiconductor manufacturing.
title Fifth Harmonic and Five-Photon Excitation Fluorescence Multiphoton Microscopy
topic Optics
url https://arxiv.org/abs/2504.20309