CBM-RAG: Demonstrating Enhanced Interpretability in Radiology Report Generation with Multi-Agent RAG and Concept Bottleneck Models

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Main Authors: Alam, Hasan Md Tusfiqur, Srivastav, Devansh, Selim, Abdulrahman Mohamed, Kadir, Md Abdul, Shuvo, Md Moktadirul Hoque, Sonntag, Daniel
Format: Preprint
Published: 2025
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author Alam, Hasan Md Tusfiqur
Srivastav, Devansh
Selim, Abdulrahman Mohamed
Kadir, Md Abdul
Shuvo, Md Moktadirul Hoque
Sonntag, Daniel
author_facet Alam, Hasan Md Tusfiqur
Srivastav, Devansh
Selim, Abdulrahman Mohamed
Kadir, Md Abdul
Shuvo, Md Moktadirul Hoque
Sonntag, Daniel
contents Advancements in generative Artificial Intelligence (AI) hold great promise for automating radiology workflows, yet challenges in interpretability and reliability hinder clinical adoption. This paper presents an automated radiology report generation framework that combines Concept Bottleneck Models (CBMs) with a Multi-Agent Retrieval-Augmented Generation (RAG) system to bridge AI performance with clinical explainability. CBMs map chest X-ray features to human-understandable clinical concepts, enabling transparent disease classification. Meanwhile, the RAG system integrates multi-agent collaboration and external knowledge to produce contextually rich, evidence-based reports. Our demonstration showcases the system's ability to deliver interpretable predictions, mitigate hallucinations, and generate high-quality, tailored reports with an interactive interface addressing accuracy, trust, and usability challenges. This framework provides a pathway to improving diagnostic consistency and empowering radiologists with actionable insights.
format Preprint
id arxiv_https___arxiv_org_abs_2504_20898
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle CBM-RAG: Demonstrating Enhanced Interpretability in Radiology Report Generation with Multi-Agent RAG and Concept Bottleneck Models
Alam, Hasan Md Tusfiqur
Srivastav, Devansh
Selim, Abdulrahman Mohamed
Kadir, Md Abdul
Shuvo, Md Moktadirul Hoque
Sonntag, Daniel
Artificial Intelligence
Computer Vision and Pattern Recognition
Information Retrieval
Advancements in generative Artificial Intelligence (AI) hold great promise for automating radiology workflows, yet challenges in interpretability and reliability hinder clinical adoption. This paper presents an automated radiology report generation framework that combines Concept Bottleneck Models (CBMs) with a Multi-Agent Retrieval-Augmented Generation (RAG) system to bridge AI performance with clinical explainability. CBMs map chest X-ray features to human-understandable clinical concepts, enabling transparent disease classification. Meanwhile, the RAG system integrates multi-agent collaboration and external knowledge to produce contextually rich, evidence-based reports. Our demonstration showcases the system's ability to deliver interpretable predictions, mitigate hallucinations, and generate high-quality, tailored reports with an interactive interface addressing accuracy, trust, and usability challenges. This framework provides a pathway to improving diagnostic consistency and empowering radiologists with actionable insights.
title CBM-RAG: Demonstrating Enhanced Interpretability in Radiology Report Generation with Multi-Agent RAG and Concept Bottleneck Models
topic Artificial Intelligence
Computer Vision and Pattern Recognition
Information Retrieval
url https://arxiv.org/abs/2504.20898