Unsupervised training of keypoint-agnostic descriptors for flexible retinal image registration

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Hauptverfasser: Rivas-Villar, David, Hervella, Álvaro S., Rouco, José, Novo, Jorge
Format: Preprint
Veröffentlicht: 2025
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author Rivas-Villar, David
Hervella, Álvaro S.
Rouco, José
Novo, Jorge
author_facet Rivas-Villar, David
Hervella, Álvaro S.
Rouco, José
Novo, Jorge
contents Current color fundus image registration approaches are limited, among other things, by the lack of labeled data, which is even more significant in the medical domain, motivating the use of unsupervised learning. Therefore, in this work, we develop a novel unsupervised descriptor learning method that does not rely on keypoint detection. This enables the resulting descriptor network to be agnostic to the keypoint detector used during the registration inference. To validate this approach, we perform an extensive and comprehensive comparison on the reference public retinal image registration dataset. Additionally, we test our method with multiple keypoint detectors of varied nature, even proposing some novel ones. Our results demonstrate that the proposed approach offers accurate registration, not incurring in any performance loss versus supervised methods. Additionally, it demonstrates accurate performance regardless of the keypoint detector used. Thus, this work represents a notable step towards leveraging unsupervised learning in the medical domain.
format Preprint
id arxiv_https___arxiv_org_abs_2505_02787
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Unsupervised training of keypoint-agnostic descriptors for flexible retinal image registration
Rivas-Villar, David
Hervella, Álvaro S.
Rouco, José
Novo, Jorge
Computer Vision and Pattern Recognition
Current color fundus image registration approaches are limited, among other things, by the lack of labeled data, which is even more significant in the medical domain, motivating the use of unsupervised learning. Therefore, in this work, we develop a novel unsupervised descriptor learning method that does not rely on keypoint detection. This enables the resulting descriptor network to be agnostic to the keypoint detector used during the registration inference. To validate this approach, we perform an extensive and comprehensive comparison on the reference public retinal image registration dataset. Additionally, we test our method with multiple keypoint detectors of varied nature, even proposing some novel ones. Our results demonstrate that the proposed approach offers accurate registration, not incurring in any performance loss versus supervised methods. Additionally, it demonstrates accurate performance regardless of the keypoint detector used. Thus, this work represents a notable step towards leveraging unsupervised learning in the medical domain.
title Unsupervised training of keypoint-agnostic descriptors for flexible retinal image registration
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2505.02787