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Autores principales: Du, Xin, Cozzi, Francesca M., Jena, Rajesh
Formato: Preprint
Publicado: 2025
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Acceso en línea:https://arxiv.org/abs/2505.03662
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author Du, Xin
Cozzi, Francesca M.
Jena, Rajesh
author_facet Du, Xin
Cozzi, Francesca M.
Jena, Rajesh
contents Fractional anisotropy (FA) and directionally encoded colour (DEC) maps are essential for evaluating white matter integrity and structural connectivity in neuroimaging. However, the spatial misalignment between FA maps and tractography atlases hinders their effective integration into predictive models. To address this issue, we propose a CycleGAN based approach for generating FA maps directly from T1-weighted MRI scans, representing the first application of this technique to both healthy and tumour-affected tissues. Our model, trained on unpaired data, produces high fidelity maps, which have been rigorously evaluated using Structural Similarity Index (SSIM) and Peak Signal-to-Noise Ratio (PSNR), demonstrating particularly robust performance in tumour regions. Radiological assessments further underscore the model's potential to enhance clinical workflows by providing an AI-driven alternative that reduces the necessity for additional scans.
format Preprint
id arxiv_https___arxiv_org_abs_2505_03662
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Revolutionizing Brain Tumor Imaging: Generating Synthetic 3D FA Maps from T1-Weighted MRI using CycleGAN Models
Du, Xin
Cozzi, Francesca M.
Jena, Rajesh
Computer Vision and Pattern Recognition
Artificial Intelligence
68U10
Fractional anisotropy (FA) and directionally encoded colour (DEC) maps are essential for evaluating white matter integrity and structural connectivity in neuroimaging. However, the spatial misalignment between FA maps and tractography atlases hinders their effective integration into predictive models. To address this issue, we propose a CycleGAN based approach for generating FA maps directly from T1-weighted MRI scans, representing the first application of this technique to both healthy and tumour-affected tissues. Our model, trained on unpaired data, produces high fidelity maps, which have been rigorously evaluated using Structural Similarity Index (SSIM) and Peak Signal-to-Noise Ratio (PSNR), demonstrating particularly robust performance in tumour regions. Radiological assessments further underscore the model's potential to enhance clinical workflows by providing an AI-driven alternative that reduces the necessity for additional scans.
title Revolutionizing Brain Tumor Imaging: Generating Synthetic 3D FA Maps from T1-Weighted MRI using CycleGAN Models
topic Computer Vision and Pattern Recognition
Artificial Intelligence
68U10
url https://arxiv.org/abs/2505.03662