Text2CT: Towards 3D CT Volume Generation from Free-text Descriptions Using Diffusion Model

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Hauptverfasser: Guo, Pengfei, Zhao, Can, Yang, Dong, He, Yufan, Nath, Vishwesh, Xu, Ziyue, Bassi, Pedro R. A. S., Zhou, Zongwei, Simon, Benjamin D., Harmon, Stephanie Anne, Turkbey, Baris, Xu, Daguang
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Veröffentlicht: 2025
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author Guo, Pengfei
Zhao, Can
Yang, Dong
He, Yufan
Nath, Vishwesh
Xu, Ziyue
Bassi, Pedro R. A. S.
Zhou, Zongwei
Simon, Benjamin D.
Harmon, Stephanie Anne
Turkbey, Baris
Xu, Daguang
author_facet Guo, Pengfei
Zhao, Can
Yang, Dong
He, Yufan
Nath, Vishwesh
Xu, Ziyue
Bassi, Pedro R. A. S.
Zhou, Zongwei
Simon, Benjamin D.
Harmon, Stephanie Anne
Turkbey, Baris
Xu, Daguang
contents Generating 3D CT volumes from descriptive free-text inputs presents a transformative opportunity in diagnostics and research. In this paper, we introduce Text2CT, a novel approach for synthesizing 3D CT volumes from textual descriptions using the diffusion model. Unlike previous methods that rely on fixed-format text input, Text2CT employs a novel prompt formulation that enables generation from diverse, free-text descriptions. The proposed framework encodes medical text into latent representations and decodes them into high-resolution 3D CT scans, effectively bridging the gap between semantic text inputs and detailed volumetric representations in a unified 3D framework. Our method demonstrates superior performance in preserving anatomical fidelity and capturing intricate structures as described in the input text. Extensive evaluations show that our approach achieves state-of-the-art results, offering promising potential applications in diagnostics, and data augmentation.
format Preprint
id arxiv_https___arxiv_org_abs_2505_04522
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Text2CT: Towards 3D CT Volume Generation from Free-text Descriptions Using Diffusion Model
Guo, Pengfei
Zhao, Can
Yang, Dong
He, Yufan
Nath, Vishwesh
Xu, Ziyue
Bassi, Pedro R. A. S.
Zhou, Zongwei
Simon, Benjamin D.
Harmon, Stephanie Anne
Turkbey, Baris
Xu, Daguang
Image and Video Processing
Computer Vision and Pattern Recognition
Generating 3D CT volumes from descriptive free-text inputs presents a transformative opportunity in diagnostics and research. In this paper, we introduce Text2CT, a novel approach for synthesizing 3D CT volumes from textual descriptions using the diffusion model. Unlike previous methods that rely on fixed-format text input, Text2CT employs a novel prompt formulation that enables generation from diverse, free-text descriptions. The proposed framework encodes medical text into latent representations and decodes them into high-resolution 3D CT scans, effectively bridging the gap between semantic text inputs and detailed volumetric representations in a unified 3D framework. Our method demonstrates superior performance in preserving anatomical fidelity and capturing intricate structures as described in the input text. Extensive evaluations show that our approach achieves state-of-the-art results, offering promising potential applications in diagnostics, and data augmentation.
title Text2CT: Towards 3D CT Volume Generation from Free-text Descriptions Using Diffusion Model
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2505.04522