Conformal Survival Bands for Risk Screening under Right-Censoring

Fuente: arXiv
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Auteurs principaux: Sesia, Matteo, Svetnik, Vladimir
Format: Preprint
Publié: 2025
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author Sesia, Matteo
Svetnik, Vladimir
author_facet Sesia, Matteo
Svetnik, Vladimir
contents We propose a method to quantify uncertainty around individual survival distribution estimates using right-censored data, compatible with any survival model. Unlike classical confidence intervals, the survival bands produced by this method offer predictive rather than population-level inference, making them useful for personalized risk screening. For example, in a low-risk screening scenario, they can be applied to flag patients whose survival band at 12 months lies entirely above 50\%, while ensuring that at least half of flagged individuals will survive past that time on average. Our approach builds on recent advances in conformal inference and integrates ideas from inverse probability of censoring weighting and multiple testing with false discovery rate control. We provide asymptotic guarantees and show promising performance in finite samples with both simulated and real data.
format Preprint
id arxiv_https___arxiv_org_abs_2505_04568
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Conformal Survival Bands for Risk Screening under Right-Censoring
Sesia, Matteo
Svetnik, Vladimir
Methodology
We propose a method to quantify uncertainty around individual survival distribution estimates using right-censored data, compatible with any survival model. Unlike classical confidence intervals, the survival bands produced by this method offer predictive rather than population-level inference, making them useful for personalized risk screening. For example, in a low-risk screening scenario, they can be applied to flag patients whose survival band at 12 months lies entirely above 50\%, while ensuring that at least half of flagged individuals will survive past that time on average. Our approach builds on recent advances in conformal inference and integrates ideas from inverse probability of censoring weighting and multiple testing with false discovery rate control. We provide asymptotic guarantees and show promising performance in finite samples with both simulated and real data.
title Conformal Survival Bands for Risk Screening under Right-Censoring
topic Methodology
url https://arxiv.org/abs/2505.04568