Mean pairwise distances in Rouse polymer subject to fast loop extrusion

Fuente: arXiv
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Auteurs principaux: Nikitin, Ilya, Masnev, Nikolay, Belan, Sergey
Format: Preprint
Publié: 2025
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author Nikitin, Ilya
Masnev, Nikolay
Belan, Sergey
author_facet Nikitin, Ilya
Masnev, Nikolay
Belan, Sergey
contents We consider a model of a Rouse polymer extended by the mechanism of active loop extrusion. The model is based on a kinetic equation that is valid provided that the extrusion rate is high enough and the resulting loop ensemble is sufficiently sparse. Within the one-loop approximation of diagrammatic calculations, a semi-analytical method for determining the mean square physical distance between a pair of chain beads as a function of the contour distance between them is developed. The model is based on a kinetic equation that is valid provided that the extrusion rate is high enough and the resulting loop ensemble is sufficiently sparse. Within the framework of the one-loop approximation of diagrammatic calculations, a semi-analytical method for determining the mean square of the physical distance between a pair of chain sections as a function of the contour distance between them is developed. The mean square of the physical distance and its logarithmic derivative as functions of the contour separation are plotted for different values of the equilibrium degree. The results are compared with the case of frozen disorder of sparse loops.
format Preprint
id arxiv_https___arxiv_org_abs_2505_05097
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Mean pairwise distances in Rouse polymer subject to fast loop extrusion
Nikitin, Ilya
Masnev, Nikolay
Belan, Sergey
Statistical Mechanics
We consider a model of a Rouse polymer extended by the mechanism of active loop extrusion. The model is based on a kinetic equation that is valid provided that the extrusion rate is high enough and the resulting loop ensemble is sufficiently sparse. Within the one-loop approximation of diagrammatic calculations, a semi-analytical method for determining the mean square physical distance between a pair of chain beads as a function of the contour distance between them is developed. The model is based on a kinetic equation that is valid provided that the extrusion rate is high enough and the resulting loop ensemble is sufficiently sparse. Within the framework of the one-loop approximation of diagrammatic calculations, a semi-analytical method for determining the mean square of the physical distance between a pair of chain sections as a function of the contour distance between them is developed. The mean square of the physical distance and its logarithmic derivative as functions of the contour separation are plotted for different values of the equilibrium degree. The results are compared with the case of frozen disorder of sparse loops.
title Mean pairwise distances in Rouse polymer subject to fast loop extrusion
topic Statistical Mechanics
url https://arxiv.org/abs/2505.05097