Integrating Explainable AI in Medical Devices: Technical, Clinical and Regulatory Insights and Recommendations

Fuente: arXiv
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Auteurs principaux: Alattal, Dima, Azar, Asal Khoshravan, Myles, Puja, Branson, Richard, Abdulhussein, Hatim, Tucker, Allan
Format: Preprint
Publié: 2025
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author Alattal, Dima
Azar, Asal Khoshravan
Myles, Puja
Branson, Richard
Abdulhussein, Hatim
Tucker, Allan
author_facet Alattal, Dima
Azar, Asal Khoshravan
Myles, Puja
Branson, Richard
Abdulhussein, Hatim
Tucker, Allan
contents There is a growing demand for the use of Artificial Intelligence (AI) and Machine Learning (ML) in healthcare, particularly as clinical decision support systems to assist medical professionals. However, the complexity of many of these models, often referred to as black box models, raises concerns about their safe integration into clinical settings as it is difficult to understand how they arrived at their predictions. This paper discusses insights and recommendations derived from an expert working group convened by the UK Medicine and Healthcare products Regulatory Agency (MHRA). The group consisted of healthcare professionals, regulators, and data scientists, with a primary focus on evaluating the outputs from different AI algorithms in clinical decision-making contexts. Additionally, the group evaluated findings from a pilot study investigating clinicians' behaviour and interaction with AI methods during clinical diagnosis. Incorporating AI methods is crucial for ensuring the safety and trustworthiness of medical AI devices in clinical settings. Adequate training for stakeholders is essential to address potential issues, and further insights and recommendations for safely adopting AI systems in healthcare settings are provided.
format Preprint
id arxiv_https___arxiv_org_abs_2505_06620
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Integrating Explainable AI in Medical Devices: Technical, Clinical and Regulatory Insights and Recommendations
Alattal, Dima
Azar, Asal Khoshravan
Myles, Puja
Branson, Richard
Abdulhussein, Hatim
Tucker, Allan
Human-Computer Interaction
Artificial Intelligence
H.5.2
There is a growing demand for the use of Artificial Intelligence (AI) and Machine Learning (ML) in healthcare, particularly as clinical decision support systems to assist medical professionals. However, the complexity of many of these models, often referred to as black box models, raises concerns about their safe integration into clinical settings as it is difficult to understand how they arrived at their predictions. This paper discusses insights and recommendations derived from an expert working group convened by the UK Medicine and Healthcare products Regulatory Agency (MHRA). The group consisted of healthcare professionals, regulators, and data scientists, with a primary focus on evaluating the outputs from different AI algorithms in clinical decision-making contexts. Additionally, the group evaluated findings from a pilot study investigating clinicians' behaviour and interaction with AI methods during clinical diagnosis. Incorporating AI methods is crucial for ensuring the safety and trustworthiness of medical AI devices in clinical settings. Adequate training for stakeholders is essential to address potential issues, and further insights and recommendations for safely adopting AI systems in healthcare settings are provided.
title Integrating Explainable AI in Medical Devices: Technical, Clinical and Regulatory Insights and Recommendations
topic Human-Computer Interaction
Artificial Intelligence
H.5.2
url https://arxiv.org/abs/2505.06620