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Main Authors: Farhadizadeh, Maryam, Weymann, Maria, Blaß, Michael, Kraus, Johann, Gundler, Christopher, Walter, Sebastian, Hempen, Noah, Binder, Harald, Binder, Nadine
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2505.06945
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author Farhadizadeh, Maryam
Weymann, Maria
Blaß, Michael
Kraus, Johann
Gundler, Christopher
Walter, Sebastian
Hempen, Noah
Binder, Harald
Binder, Nadine
author_facet Farhadizadeh, Maryam
Weymann, Maria
Blaß, Michael
Kraus, Johann
Gundler, Christopher
Walter, Sebastian
Hempen, Noah
Binder, Harald
Binder, Nadine
contents Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve diagnostic accuracy and support personalized care, modeling such heterogeneous data presents significant technical challenges. This systematic review synthesizes findings from 69 studies to identify common obstacles, including missing modalities, limited sample sizes, dimensionality imbalance, interpretability issues, and finding the optimal fusion techniques. We highlight recent methodological advances, such as transfer learning, generative models, attention mechanisms, and neural architecture search that offer promising solutions. By mapping current trends and innovations, this review provides a comprehensive overview of the field and offers practical insights to guide future research and development in multimodal modeling for medical applications.
format Preprint
id arxiv_https___arxiv_org_abs_2505_06945
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Challenges and proposed solutions in modeling multimodal data: A systematic review
Farhadizadeh, Maryam
Weymann, Maria
Blaß, Michael
Kraus, Johann
Gundler, Christopher
Walter, Sebastian
Hempen, Noah
Binder, Harald
Binder, Nadine
Machine Learning
Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve diagnostic accuracy and support personalized care, modeling such heterogeneous data presents significant technical challenges. This systematic review synthesizes findings from 69 studies to identify common obstacles, including missing modalities, limited sample sizes, dimensionality imbalance, interpretability issues, and finding the optimal fusion techniques. We highlight recent methodological advances, such as transfer learning, generative models, attention mechanisms, and neural architecture search that offer promising solutions. By mapping current trends and innovations, this review provides a comprehensive overview of the field and offers practical insights to guide future research and development in multimodal modeling for medical applications.
title Challenges and proposed solutions in modeling multimodal data: A systematic review
topic Machine Learning
url https://arxiv.org/abs/2505.06945