BioVFM-21M: Benchmarking and Scaling Self-Supervised Vision Foundation Models for Biomedical Image Analysis

Fuente: arXiv
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Autori principali: Liu, Jiarun, Zhou, Hong-Yu, Huang, Weijian, Yang, Hao, Song, Dongning, Tan, Tao, Liang, Yong, Wang, Shanshan
Natura: Preprint
Pubblicazione: 2025
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author Liu, Jiarun
Zhou, Hong-Yu
Huang, Weijian
Yang, Hao
Song, Dongning
Tan, Tao
Liang, Yong
Wang, Shanshan
author_facet Liu, Jiarun
Zhou, Hong-Yu
Huang, Weijian
Yang, Hao
Song, Dongning
Tan, Tao
Liang, Yong
Wang, Shanshan
contents Scaling up model and data size have demonstrated impressive performance improvement over a wide range of tasks. Despite extensive studies on scaling behaviors for general-purpose tasks, medical images exhibit substantial differences from natural data. It remains unclear the key factors in developing medical vision foundation models at scale due to the absence of an extensive understanding of scaling behavior in the medical domain. In this paper, we explored the scaling behavior across model sizes, training algorithms, data sizes, and imaging modalities in developing scalable medical vision foundation models by self-supervised learning. To support scalable pretraining, we introduce BioVFM-21M, a large-scale biomedical image dataset encompassing a wide range of biomedical image modalities and anatomies. We observed that scaling up does provide benefits but varies across tasks. Additional analysis reveals several factors correlated with scaling benefits. Finally, we propose BioVFM, a large-scale medical vision foundation model pretrained on 21 million biomedical images, which outperforms the previous state-of-the-art foundation models across 12 medical benchmarks. Our results highlight that while scaling up is beneficial for pursuing better performance, task characteristics, data diversity, pretraining methods, and computational efficiency remain critical considerations for developing scalable medical foundation models.
format Preprint
id arxiv_https___arxiv_org_abs_2505_09329
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle BioVFM-21M: Benchmarking and Scaling Self-Supervised Vision Foundation Models for Biomedical Image Analysis
Liu, Jiarun
Zhou, Hong-Yu
Huang, Weijian
Yang, Hao
Song, Dongning
Tan, Tao
Liang, Yong
Wang, Shanshan
Computer Vision and Pattern Recognition
Artificial Intelligence
Scaling up model and data size have demonstrated impressive performance improvement over a wide range of tasks. Despite extensive studies on scaling behaviors for general-purpose tasks, medical images exhibit substantial differences from natural data. It remains unclear the key factors in developing medical vision foundation models at scale due to the absence of an extensive understanding of scaling behavior in the medical domain. In this paper, we explored the scaling behavior across model sizes, training algorithms, data sizes, and imaging modalities in developing scalable medical vision foundation models by self-supervised learning. To support scalable pretraining, we introduce BioVFM-21M, a large-scale biomedical image dataset encompassing a wide range of biomedical image modalities and anatomies. We observed that scaling up does provide benefits but varies across tasks. Additional analysis reveals several factors correlated with scaling benefits. Finally, we propose BioVFM, a large-scale medical vision foundation model pretrained on 21 million biomedical images, which outperforms the previous state-of-the-art foundation models across 12 medical benchmarks. Our results highlight that while scaling up is beneficial for pursuing better performance, task characteristics, data diversity, pretraining methods, and computational efficiency remain critical considerations for developing scalable medical foundation models.
title BioVFM-21M: Benchmarking and Scaling Self-Supervised Vision Foundation Models for Biomedical Image Analysis
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2505.09329