Nash: Neural Adaptive Shrinkage for Structured High-Dimensional Regression

Fuente: arXiv
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Autore principale: Denault, William R. P.
Natura: Preprint
Pubblicazione: 2025
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author Denault, William R. P.
author_facet Denault, William R. P.
contents Sparse linear regression is a fundamental tool in data analysis. However, traditional approaches often fall short when covariates exhibit structure or arise from heterogeneous sources. In biomedical applications, covariates may stem from distinct modalities or be structured according to an underlying graph. We introduce \textit{Neural Adaptive Shrinkage} (Nash), a unified framework that integrates covariate-specific side information into sparse regression via neural networks. Nash adaptively modulates penalties on a per-covariate basis, learning to tailor regularization without cross-validation. We use a \textit{split variational empirical Bayes} algorithm that decouples prior learning from posterior inference, reducing the M-step from $\mathcal{O}(p) $ neural-network passes per sweep to a single batched pass, a \textit{74 to 106x wall-clock speedup} over previously proposed coordinate ascent CAVI for p between $10^2$ and $10^4$. Experiments on real data demonstrate that Nash improves accuracy and adaptability over existing methods.
format Preprint
id arxiv_https___arxiv_org_abs_2505_11143
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Nash: Neural Adaptive Shrinkage for Structured High-Dimensional Regression
Denault, William R. P.
Machine Learning
Sparse linear regression is a fundamental tool in data analysis. However, traditional approaches often fall short when covariates exhibit structure or arise from heterogeneous sources. In biomedical applications, covariates may stem from distinct modalities or be structured according to an underlying graph. We introduce \textit{Neural Adaptive Shrinkage} (Nash), a unified framework that integrates covariate-specific side information into sparse regression via neural networks. Nash adaptively modulates penalties on a per-covariate basis, learning to tailor regularization without cross-validation. We use a \textit{split variational empirical Bayes} algorithm that decouples prior learning from posterior inference, reducing the M-step from $\mathcal{O}(p) $ neural-network passes per sweep to a single batched pass, a \textit{74 to 106x wall-clock speedup} over previously proposed coordinate ascent CAVI for p between $10^2$ and $10^4$. Experiments on real data demonstrate that Nash improves accuracy and adaptability over existing methods.
title Nash: Neural Adaptive Shrinkage for Structured High-Dimensional Regression
topic Machine Learning
url https://arxiv.org/abs/2505.11143