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| Hauptverfasser: | , , , |
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| Format: | Preprint |
| Veröffentlicht: |
2025
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| Online-Zugang: | https://arxiv.org/abs/2505.12494 |
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| _version_ | 1866914278917799936 |
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| author | Hans, Atharva Singh, Abhishek Vlachos, Pavlos Bilionis, Ilias |
| author_facet | Hans, Atharva Singh, Abhishek Vlachos, Pavlos Bilionis, Ilias |
| contents | We introduce SMURF, a scalable and unsupervised machine learning method for simultaneously segmenting vascular geometries and reconstructing velocity fields from 4D flow MRI data. SMURF models geometry and velocity fields using multilayer perceptron-based functions incorporating Fourier feature embeddings and random weight factorization to accelerate convergence. A measurement model connects these fields to the observed image magnitude and phase data. Maximum likelihood estimation and subsampling enable SMURF to process high-dimensional datasets efficiently. Evaluations on synthetic, in vitro, and in vivo datasets demonstrate SMURF's performance. On synthetic internal carotid artery aneurysm data derived from CFD, SMURF achieves a quarter-voxel segmentation accuracy across noise levels of up to 50%, outperforming the state-of-the-art segmentation method by up to double the accuracy. In an in vitro experiment on Poiseuille flow, SMURF reduces velocity reconstruction RMSE by approximately 34% compared to raw measurements. In in vivo internal carotid artery aneurysm data, SMURF attains nearly half-voxel segmentation accuracy relative to expert annotations and decreases median velocity divergence residuals by about 31%, with a 27% reduction in the interquartile range. These results indicate that SMURF is robust to noise, preserves flow structure, and identifies patient-specific morphological features. SMURF advances 4D flow MRI accuracy, potentially enhancing the diagnostic utility of 4D flow MRI in clinical applications. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2505_12494 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | SMURF: Scalable method for unsupervised reconstruction of flow in 4D flow MRI Hans, Atharva Singh, Abhishek Vlachos, Pavlos Bilionis, Ilias Medical Physics We introduce SMURF, a scalable and unsupervised machine learning method for simultaneously segmenting vascular geometries and reconstructing velocity fields from 4D flow MRI data. SMURF models geometry and velocity fields using multilayer perceptron-based functions incorporating Fourier feature embeddings and random weight factorization to accelerate convergence. A measurement model connects these fields to the observed image magnitude and phase data. Maximum likelihood estimation and subsampling enable SMURF to process high-dimensional datasets efficiently. Evaluations on synthetic, in vitro, and in vivo datasets demonstrate SMURF's performance. On synthetic internal carotid artery aneurysm data derived from CFD, SMURF achieves a quarter-voxel segmentation accuracy across noise levels of up to 50%, outperforming the state-of-the-art segmentation method by up to double the accuracy. In an in vitro experiment on Poiseuille flow, SMURF reduces velocity reconstruction RMSE by approximately 34% compared to raw measurements. In in vivo internal carotid artery aneurysm data, SMURF attains nearly half-voxel segmentation accuracy relative to expert annotations and decreases median velocity divergence residuals by about 31%, with a 27% reduction in the interquartile range. These results indicate that SMURF is robust to noise, preserves flow structure, and identifies patient-specific morphological features. SMURF advances 4D flow MRI accuracy, potentially enhancing the diagnostic utility of 4D flow MRI in clinical applications. |
| title | SMURF: Scalable method for unsupervised reconstruction of flow in 4D flow MRI |
| topic | Medical Physics |
| url | https://arxiv.org/abs/2505.12494 |