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Autori principali: Alexandrov, Andrey, Acampora, Giovanni, De Lellis, Giovanni, Di Crescenzo, Antonia, Errico, Chiara, Morozova, Daria, Tioukov, Valeri, Vittiello, Autilia
Natura: Preprint
Pubblicazione: 2025
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Accesso online:https://arxiv.org/abs/2505.14754
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author Alexandrov, Andrey
Acampora, Giovanni
De Lellis, Giovanni
Di Crescenzo, Antonia
Errico, Chiara
Morozova, Daria
Tioukov, Valeri
Vittiello, Autilia
author_facet Alexandrov, Andrey
Acampora, Giovanni
De Lellis, Giovanni
Di Crescenzo, Antonia
Errico, Chiara
Morozova, Daria
Tioukov, Valeri
Vittiello, Autilia
contents Accurately tracking particles and determining their coordinate along the optical axis is a major challenge in optical microscopy, especially when extremely high precision is needed. In this study, we introduce a deep learning approach using convolutional neural networks (CNNs) that can determine axial coordinates from dual-focal-plane images without relying on predefined models. Our method achieves an axial localization precision of 40 nanometers-six times better than traditional single-focal-plane techniques. The model's simple design and strong performance make it suitable for a wide range of uses, including dark matter detection, proton therapy for cancer, and radiation protection in space. It also shows promise in fields like biological imaging, materials science, and environmental monitoring. This work highlights how machine learning can turn complex image data into reliable, precise information, offering a flexible and powerful tool for many scientific applications.
format Preprint
id arxiv_https___arxiv_org_abs_2505_14754
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Model-Independent Machine Learning Approach for Nanometric Axial Localization and Tracking
Alexandrov, Andrey
Acampora, Giovanni
De Lellis, Giovanni
Di Crescenzo, Antonia
Errico, Chiara
Morozova, Daria
Tioukov, Valeri
Vittiello, Autilia
Image and Video Processing
Instrumentation and Methods for Astrophysics
Computer Vision and Pattern Recognition
Machine Learning
Instrumentation and Detectors
Accurately tracking particles and determining their coordinate along the optical axis is a major challenge in optical microscopy, especially when extremely high precision is needed. In this study, we introduce a deep learning approach using convolutional neural networks (CNNs) that can determine axial coordinates from dual-focal-plane images without relying on predefined models. Our method achieves an axial localization precision of 40 nanometers-six times better than traditional single-focal-plane techniques. The model's simple design and strong performance make it suitable for a wide range of uses, including dark matter detection, proton therapy for cancer, and radiation protection in space. It also shows promise in fields like biological imaging, materials science, and environmental monitoring. This work highlights how machine learning can turn complex image data into reliable, precise information, offering a flexible and powerful tool for many scientific applications.
title Model-Independent Machine Learning Approach for Nanometric Axial Localization and Tracking
topic Image and Video Processing
Instrumentation and Methods for Astrophysics
Computer Vision and Pattern Recognition
Machine Learning
Instrumentation and Detectors
url https://arxiv.org/abs/2505.14754