Pre-validation Revisited

Fuente: arXiv
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Autores principales: Shang, Jing, Chatterjee, Sourav, Hastie, Trevor, Tibshirani, Robert
Formato: Preprint
Publicado: 2025
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author Shang, Jing
Chatterjee, Sourav
Hastie, Trevor
Tibshirani, Robert
author_facet Shang, Jing
Chatterjee, Sourav
Hastie, Trevor
Tibshirani, Robert
contents Pre-validation is a way to build prediction model with two datasets of significantly different feature dimensions. Previous work showed that the asymptotic distribution of the resulting test statistic for the pre-validated predictor deviates from a standard Normal, hence leads to issues in hypothesis testing. In this paper, we revisit the pre-validation procedure and extend the problem formulation without any independence assumption on the two feature sets. We propose not only an analytical distribution of the test statistic for the pre-validated predictor under certain models, but also a generic bootstrap procedure to conduct inference. We show properties and benefits of pre-validation in prediction, inference and error estimation by simulations and applications, including analysis of a breast cancer study and a synthetic GWAS example.
format Preprint
id arxiv_https___arxiv_org_abs_2505_14985
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Pre-validation Revisited
Shang, Jing
Chatterjee, Sourav
Hastie, Trevor
Tibshirani, Robert
Methodology
Machine Learning
Pre-validation is a way to build prediction model with two datasets of significantly different feature dimensions. Previous work showed that the asymptotic distribution of the resulting test statistic for the pre-validated predictor deviates from a standard Normal, hence leads to issues in hypothesis testing. In this paper, we revisit the pre-validation procedure and extend the problem formulation without any independence assumption on the two feature sets. We propose not only an analytical distribution of the test statistic for the pre-validated predictor under certain models, but also a generic bootstrap procedure to conduct inference. We show properties and benefits of pre-validation in prediction, inference and error estimation by simulations and applications, including analysis of a breast cancer study and a synthetic GWAS example.
title Pre-validation Revisited
topic Methodology
Machine Learning
url https://arxiv.org/abs/2505.14985