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Autori principali: Zhang, Yanbo, Khan, Sumeer A., Mahmud, Adnan, Yang, Huck, Lavin, Alexander, Levin, Michael, Frey, Jeremy, Dunnmon, Jared, Evans, James, Bundy, Alan, Dzeroski, Saso, Tegner, Jesper, Zenil, Hector
Natura: Preprint
Pubblicazione: 2025
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Accesso online:https://arxiv.org/abs/2505.16477
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author Zhang, Yanbo
Khan, Sumeer A.
Mahmud, Adnan
Yang, Huck
Lavin, Alexander
Levin, Michael
Frey, Jeremy
Dunnmon, Jared
Evans, James
Bundy, Alan
Dzeroski, Saso
Tegner, Jesper
Zenil, Hector
author_facet Zhang, Yanbo
Khan, Sumeer A.
Mahmud, Adnan
Yang, Huck
Lavin, Alexander
Levin, Michael
Frey, Jeremy
Dunnmon, Jared
Evans, James
Bundy, Alan
Dzeroski, Saso
Tegner, Jesper
Zenil, Hector
contents With recent Nobel Prizes recognising AI contributions to science, Large Language Models (LLMs) are transforming scientific research by enhancing productivity and reshaping the scientific method. LLMs are now involved in experimental design, data analysis, and workflows, particularly in chemistry and biology. However, challenges such as hallucinations and reliability persist. In this contribution, we review how Large Language Models (LLMs) are redefining the scientific method and explore their potential applications across different stages of the scientific cycle, from hypothesis testing to discovery. We conclude that, for LLMs to serve as relevant and effective creative engines and productivity enhancers, their deep integration into all steps of the scientific process should be pursued in collaboration and alignment with human scientific goals, with clear evaluation metrics. The transition to AI-driven science raises ethical questions about creativity, oversight, and responsibility. With careful guidance, LLMs could evolve into creative engines, driving transformative breakthroughs across scientific disciplines responsibly and effectively. However, the scientific community must also decide how much it leaves to LLMs to drive science, even when associations with 'reasoning', mostly currently undeserved, are made in exchange for the potential to explore hypothesis and solution regions that might otherwise remain unexplored by human exploration alone.
format Preprint
id arxiv_https___arxiv_org_abs_2505_16477
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Advancing the Scientific Method with Large Language Models: From Hypothesis to Discovery
Zhang, Yanbo
Khan, Sumeer A.
Mahmud, Adnan
Yang, Huck
Lavin, Alexander
Levin, Michael
Frey, Jeremy
Dunnmon, Jared
Evans, James
Bundy, Alan
Dzeroski, Saso
Tegner, Jesper
Zenil, Hector
Artificial Intelligence
With recent Nobel Prizes recognising AI contributions to science, Large Language Models (LLMs) are transforming scientific research by enhancing productivity and reshaping the scientific method. LLMs are now involved in experimental design, data analysis, and workflows, particularly in chemistry and biology. However, challenges such as hallucinations and reliability persist. In this contribution, we review how Large Language Models (LLMs) are redefining the scientific method and explore their potential applications across different stages of the scientific cycle, from hypothesis testing to discovery. We conclude that, for LLMs to serve as relevant and effective creative engines and productivity enhancers, their deep integration into all steps of the scientific process should be pursued in collaboration and alignment with human scientific goals, with clear evaluation metrics. The transition to AI-driven science raises ethical questions about creativity, oversight, and responsibility. With careful guidance, LLMs could evolve into creative engines, driving transformative breakthroughs across scientific disciplines responsibly and effectively. However, the scientific community must also decide how much it leaves to LLMs to drive science, even when associations with 'reasoning', mostly currently undeserved, are made in exchange for the potential to explore hypothesis and solution regions that might otherwise remain unexplored by human exploration alone.
title Advancing the Scientific Method with Large Language Models: From Hypothesis to Discovery
topic Artificial Intelligence
url https://arxiv.org/abs/2505.16477