Efficient Adaptive Experimentation with Noncompliance

Fuente: arXiv
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Main Authors: Oprescu, Miruna, Cho, Brian M, Kallus, Nathan
Format: Preprint
Published: 2025
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author Oprescu, Miruna
Cho, Brian M
Kallus, Nathan
author_facet Oprescu, Miruna
Cho, Brian M
Kallus, Nathan
contents We study the problem of estimating the average treatment effect (ATE) in adaptive experiments where treatment can only be encouraged -- rather than directly assigned -- via a binary instrumental variable. Building on semiparametric efficiency theory, we derive the efficiency bound for ATE estimation under arbitrary, history-dependent instrument-assignment policies, and show it is minimized by a variance-aware allocation rule that balances outcome noise and compliance variability. Leveraging this insight, we introduce AMRIV -- an Adaptive, Multiply-Robust estimator for Instrumental-Variable settings with variance-optimal assignment. AMRIV pairs (i) an online policy that adaptively approximates the optimal allocation with (ii) a sequential, influence-function-based estimator that attains the semiparametric efficiency bound while retaining multiply-robust consistency. We establish asymptotic normality, explicit convergence rates, and anytime-valid asymptotic confidence sequences that enable sequential inference. Finally, we demonstrate the practical effectiveness of our approach through empirical studies, showing that adaptive instrument assignment, when combined with the AMRIV estimator, yields improved efficiency and robustness compared to existing baselines.
format Preprint
id arxiv_https___arxiv_org_abs_2505_17468
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Efficient Adaptive Experimentation with Noncompliance
Oprescu, Miruna
Cho, Brian M
Kallus, Nathan
Methodology
Machine Learning
We study the problem of estimating the average treatment effect (ATE) in adaptive experiments where treatment can only be encouraged -- rather than directly assigned -- via a binary instrumental variable. Building on semiparametric efficiency theory, we derive the efficiency bound for ATE estimation under arbitrary, history-dependent instrument-assignment policies, and show it is minimized by a variance-aware allocation rule that balances outcome noise and compliance variability. Leveraging this insight, we introduce AMRIV -- an Adaptive, Multiply-Robust estimator for Instrumental-Variable settings with variance-optimal assignment. AMRIV pairs (i) an online policy that adaptively approximates the optimal allocation with (ii) a sequential, influence-function-based estimator that attains the semiparametric efficiency bound while retaining multiply-robust consistency. We establish asymptotic normality, explicit convergence rates, and anytime-valid asymptotic confidence sequences that enable sequential inference. Finally, we demonstrate the practical effectiveness of our approach through empirical studies, showing that adaptive instrument assignment, when combined with the AMRIV estimator, yields improved efficiency and robustness compared to existing baselines.
title Efficient Adaptive Experimentation with Noncompliance
topic Methodology
Machine Learning
url https://arxiv.org/abs/2505.17468