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Main Authors: Wu, Jiangjie, Chen, Lixuan, Li, Zhenghao, Li, Xin, Ozturk, Saban, Wang, Lihui, Wang, Rongpin, Wei, Hongjiang, Zhang, Yuyao
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2505.17472
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author Wu, Jiangjie
Chen, Lixuan
Li, Zhenghao
Li, Xin
Ozturk, Saban
Wang, Lihui
Wang, Rongpin
Wei, Hongjiang
Zhang, Yuyao
author_facet Wu, Jiangjie
Chen, Lixuan
Li, Zhenghao
Li, Xin
Ozturk, Saban
Wang, Lihui
Wang, Rongpin
Wei, Hongjiang
Zhang, Yuyao
contents High-quality 3D fetal brain MRI reconstruction from motion-corrupted 2D slices is crucial for clinical diagnosis. Reliable slice-to-volume registration (SVR)-based motion correction and super-resolution reconstruction (SRR) methods are essential. Deep learning (DL) has demonstrated potential in enhancing SVR and SRR when compared to conventional methods. However, it requires large-scale external training datasets, which are difficult to obtain for clinical fetal MRI. To address this issue, we propose an unsupervised iterative SVR-SRR framework for isotropic HR volume reconstruction. Specifically, SVR is formulated as a function mapping a 2D slice and a 3D target volume to a rigid transformation matrix, which aligns the slice to the underlying location in the target volume. The function is parameterized by a convolutional neural network, which is trained by minimizing the difference between the volume slicing at the predicted position and the input slice. In SRR, a decoding network embedded within a deep image prior framework is incorporated with a comprehensive image degradation model to produce the high-resolution (HR) volume. The deep image prior framework offers a local consistency prior to guide the reconstruction of HR volumes. By performing a forward degradation model, the HR volume is optimized by minimizing loss between predicted slices and the observed slices. Comprehensive experiments conducted on large-magnitude motion-corrupted simulation data and clinical data demonstrate the superior performance of the proposed framework over state-of-the-art fetal brain reconstruction frameworks.
format Preprint
id arxiv_https___arxiv_org_abs_2505_17472
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle SUFFICIENT: A scan-specific unsupervised deep learning framework for high-resolution 3D isotropic fetal brain MRI reconstruction
Wu, Jiangjie
Chen, Lixuan
Li, Zhenghao
Li, Xin
Ozturk, Saban
Wang, Lihui
Wang, Rongpin
Wei, Hongjiang
Zhang, Yuyao
Image and Video Processing
Computer Vision and Pattern Recognition
High-quality 3D fetal brain MRI reconstruction from motion-corrupted 2D slices is crucial for clinical diagnosis. Reliable slice-to-volume registration (SVR)-based motion correction and super-resolution reconstruction (SRR) methods are essential. Deep learning (DL) has demonstrated potential in enhancing SVR and SRR when compared to conventional methods. However, it requires large-scale external training datasets, which are difficult to obtain for clinical fetal MRI. To address this issue, we propose an unsupervised iterative SVR-SRR framework for isotropic HR volume reconstruction. Specifically, SVR is formulated as a function mapping a 2D slice and a 3D target volume to a rigid transformation matrix, which aligns the slice to the underlying location in the target volume. The function is parameterized by a convolutional neural network, which is trained by minimizing the difference between the volume slicing at the predicted position and the input slice. In SRR, a decoding network embedded within a deep image prior framework is incorporated with a comprehensive image degradation model to produce the high-resolution (HR) volume. The deep image prior framework offers a local consistency prior to guide the reconstruction of HR volumes. By performing a forward degradation model, the HR volume is optimized by minimizing loss between predicted slices and the observed slices. Comprehensive experiments conducted on large-magnitude motion-corrupted simulation data and clinical data demonstrate the superior performance of the proposed framework over state-of-the-art fetal brain reconstruction frameworks.
title SUFFICIENT: A scan-specific unsupervised deep learning framework for high-resolution 3D isotropic fetal brain MRI reconstruction
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2505.17472