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Hauptverfasser: Li, Xingyu, Liu, Qing, Jiang, Tony, Xia, Hong Amy, Hobbs, Brian P., Wei, Peng
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2505.17917
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author Li, Xingyu
Liu, Qing
Jiang, Tony
Xia, Hong Amy
Hobbs, Brian P.
Wei, Peng
author_facet Li, Xingyu
Liu, Qing
Jiang, Tony
Xia, Hong Amy
Hobbs, Brian P.
Wei, Peng
contents We propose a novel method, termed the M-learner, for estimating heterogeneous indirect and total treatment effects and identifying relevant subgroups within a mediation framework. The procedure comprises four key steps. First, we compute individual-level conditional average indirect/total treatment effect Second, we construct a distance matrix based on pairwise differences. Third, we apply tSNE to project this matrix into a low-dimensional Euclidean space, followed by K-means clustering to identify subgroup structures. Finally, we calibrate and refine the clusters using a threshold-based procedure to determine the optimal configuration. To the best of our knowledge, this is the first approach specifically designed to capture treatment effect heterogeneity in the presence of mediation. Experimental results validate the robustness and effectiveness of the proposed framework. Application to the real-world Jobs II dataset highlights the broad adaptability and potential applicability of our method.Code is available at https: //anonymous.4open.science/r/M-learner-C4BB.
format Preprint
id arxiv_https___arxiv_org_abs_2505_17917
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle M-learner:A Flexible And Powerful Framework To Study Heterogeneous Treatment Effect In Mediation Model
Li, Xingyu
Liu, Qing
Jiang, Tony
Xia, Hong Amy
Hobbs, Brian P.
Wei, Peng
Machine Learning
Methodology
We propose a novel method, termed the M-learner, for estimating heterogeneous indirect and total treatment effects and identifying relevant subgroups within a mediation framework. The procedure comprises four key steps. First, we compute individual-level conditional average indirect/total treatment effect Second, we construct a distance matrix based on pairwise differences. Third, we apply tSNE to project this matrix into a low-dimensional Euclidean space, followed by K-means clustering to identify subgroup structures. Finally, we calibrate and refine the clusters using a threshold-based procedure to determine the optimal configuration. To the best of our knowledge, this is the first approach specifically designed to capture treatment effect heterogeneity in the presence of mediation. Experimental results validate the robustness and effectiveness of the proposed framework. Application to the real-world Jobs II dataset highlights the broad adaptability and potential applicability of our method.Code is available at https: //anonymous.4open.science/r/M-learner-C4BB.
title M-learner:A Flexible And Powerful Framework To Study Heterogeneous Treatment Effect In Mediation Model
topic Machine Learning
Methodology
url https://arxiv.org/abs/2505.17917