Signal, Image, or Symbolic: Exploring the Best Input Representation for Electrocardiogram-Language Models Through a Unified Framework

Fuente: arXiv
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Autori principali: Han, William, Duan, Chaojing, Cen, Zhepeng, Yao, Yihang, Song, Xiaoyu, Mhaskar, Atharva, Leong, Dylan, Rosenberg, Michael A., Liu, Emerson, Zhao, Ding
Natura: Preprint
Pubblicazione: 2025
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author Han, William
Duan, Chaojing
Cen, Zhepeng
Yao, Yihang
Song, Xiaoyu
Mhaskar, Atharva
Leong, Dylan
Rosenberg, Michael A.
Liu, Emerson
Zhao, Ding
author_facet Han, William
Duan, Chaojing
Cen, Zhepeng
Yao, Yihang
Song, Xiaoyu
Mhaskar, Atharva
Leong, Dylan
Rosenberg, Michael A.
Liu, Emerson
Zhao, Ding
contents Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively generates a free-form textual response. Unlike traditional classification-based systems, ELMs emulate expert cardiac electrophysiologists by issuing diagnoses, analyzing waveform morphology, identifying contributing factors, and proposing patient-specific action plans. To realize this potential, researchers are curating instruction-tuning datasets that pair ECGs with textual dialogues and are training ELMs on these resources. Yet before scaling ELMs further, there is a fundamental question yet to be explored: What is the most effective ECG input representation? In recent works, three candidate representations have emerged-raw time-series signals, rendered images, and discretized symbolic sequences. We present the first comprehensive benchmark of these modalities across 6 public datasets and 5 evaluation metrics. We find symbolic representations achieve the greatest number of statistically significant wins over both signal and image inputs. We further ablate the LLM backbone, ECG duration, and token budget, and we evaluate robustness to signal perturbations. We hope that our findings offer clear guidance for selecting input representations when developing the next generation of ELMs.
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id arxiv_https___arxiv_org_abs_2505_18847
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Signal, Image, or Symbolic: Exploring the Best Input Representation for Electrocardiogram-Language Models Through a Unified Framework
Han, William
Duan, Chaojing
Cen, Zhepeng
Yao, Yihang
Song, Xiaoyu
Mhaskar, Atharva
Leong, Dylan
Rosenberg, Michael A.
Liu, Emerson
Zhao, Ding
Artificial Intelligence
Computation and Language
Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively generates a free-form textual response. Unlike traditional classification-based systems, ELMs emulate expert cardiac electrophysiologists by issuing diagnoses, analyzing waveform morphology, identifying contributing factors, and proposing patient-specific action plans. To realize this potential, researchers are curating instruction-tuning datasets that pair ECGs with textual dialogues and are training ELMs on these resources. Yet before scaling ELMs further, there is a fundamental question yet to be explored: What is the most effective ECG input representation? In recent works, three candidate representations have emerged-raw time-series signals, rendered images, and discretized symbolic sequences. We present the first comprehensive benchmark of these modalities across 6 public datasets and 5 evaluation metrics. We find symbolic representations achieve the greatest number of statistically significant wins over both signal and image inputs. We further ablate the LLM backbone, ECG duration, and token budget, and we evaluate robustness to signal perturbations. We hope that our findings offer clear guidance for selecting input representations when developing the next generation of ELMs.
title Signal, Image, or Symbolic: Exploring the Best Input Representation for Electrocardiogram-Language Models Through a Unified Framework
topic Artificial Intelligence
Computation and Language
url https://arxiv.org/abs/2505.18847