Active Matter under Cyclic Stretch: Modeling Microtubule Alignment and Bundling

Fuente: arXiv
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Main Authors: Tagaki, Takumi, Nishikawa, Seiya, Ishihara, Shuji
Format: Preprint
Published: 2025
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author Tagaki, Takumi
Nishikawa, Seiya
Ishihara, Shuji
author_facet Tagaki, Takumi
Nishikawa, Seiya
Ishihara, Shuji
contents We investigate the behavior of self-propelled particles under cyclic stretching, inspired by the characteristic pattern dynamics observed in microtubule (MT) motility assays subjected to uniaxial cyclic substrate stretching. We develop a self-propelled particle model that incorporates the elastic energy acting on the filaments due to substrate deformation, successfully reproducing the experimentally observed MT patterns. Additionally, the general framework of the model enables systematic exploration of collective responses to various substrate deformations, offering potential applications in the manipulation of MT patterns and other active matter systems.
format Preprint
id arxiv_https___arxiv_org_abs_2505_19127
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Active Matter under Cyclic Stretch: Modeling Microtubule Alignment and Bundling
Tagaki, Takumi
Nishikawa, Seiya
Ishihara, Shuji
Soft Condensed Matter
Biomolecules
Subcellular Processes
We investigate the behavior of self-propelled particles under cyclic stretching, inspired by the characteristic pattern dynamics observed in microtubule (MT) motility assays subjected to uniaxial cyclic substrate stretching. We develop a self-propelled particle model that incorporates the elastic energy acting on the filaments due to substrate deformation, successfully reproducing the experimentally observed MT patterns. Additionally, the general framework of the model enables systematic exploration of collective responses to various substrate deformations, offering potential applications in the manipulation of MT patterns and other active matter systems.
title Active Matter under Cyclic Stretch: Modeling Microtubule Alignment and Bundling
topic Soft Condensed Matter
Biomolecules
Subcellular Processes
url https://arxiv.org/abs/2505.19127