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Auteurs principaux: Yin, Ming, Qu, Yuanhao, Yang, Ling, Cong, Le, Wang, Mengdi
Format: Preprint
Publié: 2025
Sujets:
Accès en ligne:https://arxiv.org/abs/2505.19501
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author Yin, Ming
Qu, Yuanhao
Yang, Ling
Cong, Le
Wang, Mengdi
author_facet Yin, Ming
Qu, Yuanhao
Yang, Ling
Cong, Le
Wang, Mengdi
contents We investigate how to teach large language models (LLMs) to perform scientific reasoning by leveraging expert discussions as a learning signal. Focusing on the genomics domain, we develop an automated pipeline to extract trainable data and introduce Genome-Bench, a new benchmark constructed from over a decade of scientific forum discussions on genome engineering. Our pipeline transforms raw interactions into a reinforcement learning-friendly multiple-choice questions format, supported by 3000+ high-quality question-answer pairs spanning foundational biology, experimental troubleshooting, tool usage, and beyond. We fine-tune an LLM using RL with a rule-based reward signal derived from the synthetic MCQ dataset to enhance domain-specific reasoning. Our results show that reinforcement learning from scientific discussions improves model performance by over 15% compared to the base model on Genome-Bench, narrowing the gap between open-source LLMs and expert-level reasoning. To our knowledge, this is the first end-to-end pipeline for teaching LLMs to reason from scientific discussions, with promising potential for generalization across scientific domains beyond biology.
format Preprint
id arxiv_https___arxiv_org_abs_2505_19501
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Toward Scientific Reasoning in LLMs: Training from Expert Discussions via Reinforcement Learning
Yin, Ming
Qu, Yuanhao
Yang, Ling
Cong, Le
Wang, Mengdi
Artificial Intelligence
We investigate how to teach large language models (LLMs) to perform scientific reasoning by leveraging expert discussions as a learning signal. Focusing on the genomics domain, we develop an automated pipeline to extract trainable data and introduce Genome-Bench, a new benchmark constructed from over a decade of scientific forum discussions on genome engineering. Our pipeline transforms raw interactions into a reinforcement learning-friendly multiple-choice questions format, supported by 3000+ high-quality question-answer pairs spanning foundational biology, experimental troubleshooting, tool usage, and beyond. We fine-tune an LLM using RL with a rule-based reward signal derived from the synthetic MCQ dataset to enhance domain-specific reasoning. Our results show that reinforcement learning from scientific discussions improves model performance by over 15% compared to the base model on Genome-Bench, narrowing the gap between open-source LLMs and expert-level reasoning. To our knowledge, this is the first end-to-end pipeline for teaching LLMs to reason from scientific discussions, with promising potential for generalization across scientific domains beyond biology.
title Toward Scientific Reasoning in LLMs: Training from Expert Discussions via Reinforcement Learning
topic Artificial Intelligence
url https://arxiv.org/abs/2505.19501