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Main Authors: Kokash, Natallia, Wang, Lei, Gillespie, Thomas H., Belloum, Adam, Grosso, Paola, Quinney, Sara, Li, Lang, de Bono, Bernard
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2505.20020
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author Kokash, Natallia
Wang, Lei
Gillespie, Thomas H.
Belloum, Adam
Grosso, Paola
Quinney, Sara
Li, Lang
de Bono, Bernard
author_facet Kokash, Natallia
Wang, Lei
Gillespie, Thomas H.
Belloum, Adam
Grosso, Paola
Quinney, Sara
Li, Lang
de Bono, Bernard
contents The rise of electronic health records (EHRs) has unlocked new opportunities for medical research, but privacy regulations and data heterogeneity remain key barriers to large-scale machine learning. Federated learning (FL) enables collaborative modeling without sharing raw data, yet faces challenges in harmonizing diverse clinical datasets. This paper presents a two-step data alignment strategy integrating ontologies and large language models (LLMs) to support secure, privacy-preserving FL in healthcare, demonstrating its effectiveness in a real-world project involving semantic mapping of EHR data.
format Preprint
id arxiv_https___arxiv_org_abs_2505_20020
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Ontology- and LLM-based Data Harmonization for Federated Learning in Healthcare
Kokash, Natallia
Wang, Lei
Gillespie, Thomas H.
Belloum, Adam
Grosso, Paola
Quinney, Sara
Li, Lang
de Bono, Bernard
Machine Learning
Software Engineering
The rise of electronic health records (EHRs) has unlocked new opportunities for medical research, but privacy regulations and data heterogeneity remain key barriers to large-scale machine learning. Federated learning (FL) enables collaborative modeling without sharing raw data, yet faces challenges in harmonizing diverse clinical datasets. This paper presents a two-step data alignment strategy integrating ontologies and large language models (LLMs) to support secure, privacy-preserving FL in healthcare, demonstrating its effectiveness in a real-world project involving semantic mapping of EHR data.
title Ontology- and LLM-based Data Harmonization for Federated Learning in Healthcare
topic Machine Learning
Software Engineering
url https://arxiv.org/abs/2505.20020