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Hauptverfasser: Noroozizadeh, Shahriar, Kumar, Sayantan, Chen, George H., Weiss, Jeremy C.
Format: Preprint
Veröffentlicht: 2025
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Online-Zugang:https://arxiv.org/abs/2505.20323
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author Noroozizadeh, Shahriar
Kumar, Sayantan
Chen, George H.
Weiss, Jeremy C.
author_facet Noroozizadeh, Shahriar
Kumar, Sayantan
Chen, George H.
Weiss, Jeremy C.
contents Clinical narratives encode temporal dynamics essential for modeling patient trajectories, yet large-scale temporally annotated resources are scarce. We introduce PMOA-TTS, a corpus of 124,699 single-patient PubMed Open Access case reports converted into structured textual timelines of (event, time) pairs using a scalable large-language-model pipeline (Llama 3.3 70B and DeepSeek-R1). The corpus comprises over 5.6 million timestamped events, alongside extracted demographics and diagnoses. Technical validation uses a clinician-curated gold set and three measures: semantic event matching, temporal concordance (c-index), and alignment error summarized with Area Under the Log-Time CDF (AULTC). We benchmark alternative prompting and model choices and provide documentation to support reproduction. PMOA-TTS enables research on timeline extraction, temporal reasoning, survival modeling and event forecasting from narrative text, and offers broad diagnostic and demographic coverage. Data and code are openly available in public repositories.
format Preprint
id arxiv_https___arxiv_org_abs_2505_20323
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle PMOA-TTS: Introducing the PubMed Open Access Textual Times Series Corpus
Noroozizadeh, Shahriar
Kumar, Sayantan
Chen, George H.
Weiss, Jeremy C.
Computation and Language
Artificial Intelligence
Machine Learning
Clinical narratives encode temporal dynamics essential for modeling patient trajectories, yet large-scale temporally annotated resources are scarce. We introduce PMOA-TTS, a corpus of 124,699 single-patient PubMed Open Access case reports converted into structured textual timelines of (event, time) pairs using a scalable large-language-model pipeline (Llama 3.3 70B and DeepSeek-R1). The corpus comprises over 5.6 million timestamped events, alongside extracted demographics and diagnoses. Technical validation uses a clinician-curated gold set and three measures: semantic event matching, temporal concordance (c-index), and alignment error summarized with Area Under the Log-Time CDF (AULTC). We benchmark alternative prompting and model choices and provide documentation to support reproduction. PMOA-TTS enables research on timeline extraction, temporal reasoning, survival modeling and event forecasting from narrative text, and offers broad diagnostic and demographic coverage. Data and code are openly available in public repositories.
title PMOA-TTS: Introducing the PubMed Open Access Textual Times Series Corpus
topic Computation and Language
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2505.20323