Exploring Scaling Laws for EHR Foundation Models

Fuente: arXiv
Guardado en:
Detalles Bibliográficos
Autores principales: Zhang, Sheng, Liu, Qin, Usuyama, Naoto, Wong, Cliff, Naumann, Tristan, Poon, Hoifung
Formato: Preprint
Publicado: 2025
Materias:
Acceso en línea:
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
_version_ 1866916894971265024
author Zhang, Sheng
Liu, Qin
Usuyama, Naoto
Wong, Cliff
Naumann, Tristan
Poon, Hoifung
author_facet Zhang, Sheng
Liu, Qin
Usuyama, Naoto
Wong, Cliff
Naumann, Tristan
Poon, Hoifung
contents The emergence of scaling laws has profoundly shaped the development of large language models (LLMs), enabling predictable performance gains through systematic increases in model size, dataset volume, and compute. Yet, these principles remain largely unexplored in the context of electronic health records (EHRs) -- a rich, sequential, and globally abundant data source that differs structurally from natural language. In this work, we present the first empirical investigation of scaling laws for EHR foundation models. By training transformer architectures on patient timeline data from the MIMIC-IV database across varying model sizes and compute budgets, we identify consistent scaling patterns, including parabolic IsoFLOPs curves and power-law relationships between compute, model parameters, data size, and clinical utility. These findings demonstrate that EHR models exhibit scaling behavior analogous to LLMs, offering predictive insights into resource-efficient training strategies. Our results lay the groundwork for developing powerful EHR foundation models capable of transforming clinical prediction tasks and advancing personalized healthcare.
format Preprint
id arxiv_https___arxiv_org_abs_2505_22964
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Exploring Scaling Laws for EHR Foundation Models
Zhang, Sheng
Liu, Qin
Usuyama, Naoto
Wong, Cliff
Naumann, Tristan
Poon, Hoifung
Computation and Language
Artificial Intelligence
Machine Learning
The emergence of scaling laws has profoundly shaped the development of large language models (LLMs), enabling predictable performance gains through systematic increases in model size, dataset volume, and compute. Yet, these principles remain largely unexplored in the context of electronic health records (EHRs) -- a rich, sequential, and globally abundant data source that differs structurally from natural language. In this work, we present the first empirical investigation of scaling laws for EHR foundation models. By training transformer architectures on patient timeline data from the MIMIC-IV database across varying model sizes and compute budgets, we identify consistent scaling patterns, including parabolic IsoFLOPs curves and power-law relationships between compute, model parameters, data size, and clinical utility. These findings demonstrate that EHR models exhibit scaling behavior analogous to LLMs, offering predictive insights into resource-efficient training strategies. Our results lay the groundwork for developing powerful EHR foundation models capable of transforming clinical prediction tasks and advancing personalized healthcare.
title Exploring Scaling Laws for EHR Foundation Models
topic Computation and Language
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2505.22964