Helmet ultrasound for brain imaging in post-hemicraniectomy patients
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arXiv
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| Main Authors: | , , , , , , |
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| Format: | Preprint |
| Published: |
2025
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| _version_ | 1866910978306736128 |
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| author | Zhang, Yang Sastry, Karteekeya Rossi, Iyla Olick-Gibson, Joshua Russin, Jonathan J. Liu, Charles Y. Wang, Lihong V. |
| author_facet | Zhang, Yang Sastry, Karteekeya Rossi, Iyla Olick-Gibson, Joshua Russin, Jonathan J. Liu, Charles Y. Wang, Lihong V. |
| contents | Noninvasive imaging deep into the adult brain at submillimeter and millisecond scales remains a challenge in medical imaging. Here, we report a helmet based ultrasound brain imager built from a customized helmet, a scanned ultrasound array, and three dimensional printing for real time imaging of human brain anatomical and functional information. Through its application to post hemicraniectomy patients in a sitting position, we achieved volumetric brain tissue structural, vascular, and blood flow images at centimeter scale depths with submillimeter and millisecond spatiotemporal resolutions. We also demonstrated the system capability to track cerebral blood flow over repeated imaging sessions, including during motion prone conditions. Our brain imager circumvents the skull and bridges the gap between high resolution human brain imaging and wearable convenience. This imager may serve as a platform for further investigations into human brain dynamics in post hemicraniectomy patients and offer insights into the brain that could surpass those obtained from non human primate studies. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2506_00626 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Helmet ultrasound for brain imaging in post-hemicraniectomy patients Zhang, Yang Sastry, Karteekeya Rossi, Iyla Olick-Gibson, Joshua Russin, Jonathan J. Liu, Charles Y. Wang, Lihong V. Medical Physics Signal Processing Noninvasive imaging deep into the adult brain at submillimeter and millisecond scales remains a challenge in medical imaging. Here, we report a helmet based ultrasound brain imager built from a customized helmet, a scanned ultrasound array, and three dimensional printing for real time imaging of human brain anatomical and functional information. Through its application to post hemicraniectomy patients in a sitting position, we achieved volumetric brain tissue structural, vascular, and blood flow images at centimeter scale depths with submillimeter and millisecond spatiotemporal resolutions. We also demonstrated the system capability to track cerebral blood flow over repeated imaging sessions, including during motion prone conditions. Our brain imager circumvents the skull and bridges the gap between high resolution human brain imaging and wearable convenience. This imager may serve as a platform for further investigations into human brain dynamics in post hemicraniectomy patients and offer insights into the brain that could surpass those obtained from non human primate studies. |
| title | Helmet ultrasound for brain imaging in post-hemicraniectomy patients |
| topic | Medical Physics Signal Processing |
| url | https://arxiv.org/abs/2506.00626 |