Improved Risk Ratio Approximation by Complementary Log-Log Models: A Comparison with Logistic Models

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Autori principali: Tsubota, Yuji, Beppu, Kenji
Natura: Preprint
Pubblicazione: 2025
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author Tsubota, Yuji
Beppu, Kenji
author_facet Tsubota, Yuji
Beppu, Kenji
contents Odds ratios obtained from logistic models fail to approximate risk ratios with common outcomes, leading to potential misinterpretations about exposure effects by practitioners. This article investigates the complementary log-log models as a practical alternative to produce risk ratio approximation. We demonstrate that the corresponding effect measure of complementary log-log models, called the complementary log ratio in this article, consistently provides a closer approximation to risk ratios than odds ratios. To compare the approximation accuracy, we adopt the one-parameter Aranda-Ordaz family of link functions, which includes both the logit and complementary log-log link functions as special cases. Within this unified framework, we implement a theoretical comparison of approximation accuracy between the complementary log ratio and the odds ratio, showing that the former always produces smaller approximation bias. Simulation studies further reinforce our theoretical findings. Given that the complementary log-log model is easily implemented in standard statistical software such as R and SAS, we encourage more frequent use of this model as a simple and effective alternative to logistic models when the goal is to approximate risk ratios more accurately.
format Preprint
id arxiv_https___arxiv_org_abs_2506_00889
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Improved Risk Ratio Approximation by Complementary Log-Log Models: A Comparison with Logistic Models
Tsubota, Yuji
Beppu, Kenji
Methodology
Applications
Odds ratios obtained from logistic models fail to approximate risk ratios with common outcomes, leading to potential misinterpretations about exposure effects by practitioners. This article investigates the complementary log-log models as a practical alternative to produce risk ratio approximation. We demonstrate that the corresponding effect measure of complementary log-log models, called the complementary log ratio in this article, consistently provides a closer approximation to risk ratios than odds ratios. To compare the approximation accuracy, we adopt the one-parameter Aranda-Ordaz family of link functions, which includes both the logit and complementary log-log link functions as special cases. Within this unified framework, we implement a theoretical comparison of approximation accuracy between the complementary log ratio and the odds ratio, showing that the former always produces smaller approximation bias. Simulation studies further reinforce our theoretical findings. Given that the complementary log-log model is easily implemented in standard statistical software such as R and SAS, we encourage more frequent use of this model as a simple and effective alternative to logistic models when the goal is to approximate risk ratios more accurately.
title Improved Risk Ratio Approximation by Complementary Log-Log Models: A Comparison with Logistic Models
topic Methodology
Applications
url https://arxiv.org/abs/2506.00889