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Main Authors: Ryu, Howon, Chen, Yuliang, Wang, Yacun, LaCroix, Andrea Z., Di, Chongzhi, Natarajan, Loki, Wang, Yu, Zou, Jingjing
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2506.02260
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author Ryu, Howon
Chen, Yuliang
Wang, Yacun
LaCroix, Andrea Z.
Di, Chongzhi
Natarajan, Loki
Wang, Yu
Zou, Jingjing
author_facet Ryu, Howon
Chen, Yuliang
Wang, Yacun
LaCroix, Andrea Z.
Di, Chongzhi
Natarajan, Loki
Wang, Yu
Zou, Jingjing
contents Wearable devices enable continuous multi-modal physiological and behavioral monitoring, yet analysis of these data streams faces fundamental challenges including the lack of gold-standard labels and incomplete sensor data. While self-supervised learning approaches have shown promise for addressing these issues, existing multi-modal extensions present opportunities to better leverage the rich temporal and cross-modal correlations inherent in simultaneously recorded wearable sensor data. We propose the Multi-modal Cross-masked Autoencoder (MoCA), a self-supervised learning framework that combines transformer architecture with masked autoencoder (MAE) methodology, using a principled cross-modality masking scheme that explicitly leverages correlation structures between sensor modalities. MoCA demonstrates strong performance boosts across reconstruction and downstream classification tasks on diverse benchmark datasets. We further establish theoretical guarantees by establishing a fundamental connection between multi-modal MAE loss and kernelized canonical correlation analysis through a Reproducing Kernel Hilbert Space framework, providing principled guidance for correlation-aware masking strategy design. Our approach offers a novel solution for leveraging unlabeled multi-modal wearable data while handling missing modalities, with broad applications across digital health domains.
format Preprint
id arxiv_https___arxiv_org_abs_2506_02260
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MoCA: Multi-modal Cross-masked Autoencoder for Digital Health Measurements
Ryu, Howon
Chen, Yuliang
Wang, Yacun
LaCroix, Andrea Z.
Di, Chongzhi
Natarajan, Loki
Wang, Yu
Zou, Jingjing
Machine Learning
Applications
Wearable devices enable continuous multi-modal physiological and behavioral monitoring, yet analysis of these data streams faces fundamental challenges including the lack of gold-standard labels and incomplete sensor data. While self-supervised learning approaches have shown promise for addressing these issues, existing multi-modal extensions present opportunities to better leverage the rich temporal and cross-modal correlations inherent in simultaneously recorded wearable sensor data. We propose the Multi-modal Cross-masked Autoencoder (MoCA), a self-supervised learning framework that combines transformer architecture with masked autoencoder (MAE) methodology, using a principled cross-modality masking scheme that explicitly leverages correlation structures between sensor modalities. MoCA demonstrates strong performance boosts across reconstruction and downstream classification tasks on diverse benchmark datasets. We further establish theoretical guarantees by establishing a fundamental connection between multi-modal MAE loss and kernelized canonical correlation analysis through a Reproducing Kernel Hilbert Space framework, providing principled guidance for correlation-aware masking strategy design. Our approach offers a novel solution for leveraging unlabeled multi-modal wearable data while handling missing modalities, with broad applications across digital health domains.
title MoCA: Multi-modal Cross-masked Autoencoder for Digital Health Measurements
topic Machine Learning
Applications
url https://arxiv.org/abs/2506.02260