DLiPath: A Benchmark for the Comprehensive Assessment of Donor Liver Based on Histopathological Image Dataset

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Hauptverfasser: Pan, Liangrui, Li, Xingchen, Chen, Zhongyi, Chu, Ling, Peng, Shaoliang
Format: Preprint
Veröffentlicht: 2025
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author Pan, Liangrui
Li, Xingchen
Chen, Zhongyi
Chu, Ling
Peng, Shaoliang
author_facet Pan, Liangrui
Li, Xingchen
Chen, Zhongyi
Chu, Ling
Peng, Shaoliang
contents Pathologists comprehensive evaluation of donor liver biopsies provides crucial information for accepting or discarding potential grafts. However, rapidly and accurately obtaining these assessments intraoperatively poses a significant challenge for pathologists. Features in donor liver biopsies, such as portal tract fibrosis, total steatosis, macrovesicular steatosis, and hepatocellular ballooning are correlated with transplant outcomes, yet quantifying these indicators suffers from substantial inter- and intra-observer variability. To address this, we introduce DLiPath, the first benchmark for comprehensive donor liver assessment based on a histopathology image dataset. We collected and publicly released 636 whole slide images from 304 donor liver patients at the Department of Pathology, the Third Xiangya Hospital, with expert annotations for key pathological features (including cholestasis, portal tract fibrosis, portal inflammation, total steatosis, macrovesicular steatosis, and hepatocellular ballooning). We selected nine state-of-the-art multiple-instance learning (MIL) models based on the DLiPath dataset as baselines for extensive comparative analysis. The experimental results demonstrate that several MIL models achieve high accuracy across donor liver assessment indicators on DLiPath, charting a clear course for future automated and intelligent donor liver assessment research. Data and code are available at https://github.com/panliangrui/ACM_MM_2025.
format Preprint
id arxiv_https___arxiv_org_abs_2506_03185
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle DLiPath: A Benchmark for the Comprehensive Assessment of Donor Liver Based on Histopathological Image Dataset
Pan, Liangrui
Li, Xingchen
Chen, Zhongyi
Chu, Ling
Peng, Shaoliang
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Quantitative Methods
Pathologists comprehensive evaluation of donor liver biopsies provides crucial information for accepting or discarding potential grafts. However, rapidly and accurately obtaining these assessments intraoperatively poses a significant challenge for pathologists. Features in donor liver biopsies, such as portal tract fibrosis, total steatosis, macrovesicular steatosis, and hepatocellular ballooning are correlated with transplant outcomes, yet quantifying these indicators suffers from substantial inter- and intra-observer variability. To address this, we introduce DLiPath, the first benchmark for comprehensive donor liver assessment based on a histopathology image dataset. We collected and publicly released 636 whole slide images from 304 donor liver patients at the Department of Pathology, the Third Xiangya Hospital, with expert annotations for key pathological features (including cholestasis, portal tract fibrosis, portal inflammation, total steatosis, macrovesicular steatosis, and hepatocellular ballooning). We selected nine state-of-the-art multiple-instance learning (MIL) models based on the DLiPath dataset as baselines for extensive comparative analysis. The experimental results demonstrate that several MIL models achieve high accuracy across donor liver assessment indicators on DLiPath, charting a clear course for future automated and intelligent donor liver assessment research. Data and code are available at https://github.com/panliangrui/ACM_MM_2025.
title DLiPath: A Benchmark for the Comprehensive Assessment of Donor Liver Based on Histopathological Image Dataset
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Quantitative Methods
url https://arxiv.org/abs/2506.03185