Transient osmotic flows in a microfluidic channel: measurements of solute permeability and reflection coefficients of hydrogel membranes
Fuente:
arXiv
Salvato in:
| Autori principali: | , , |
|---|---|
| Natura: | Preprint |
| Pubblicazione: |
2025
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1866916782460108800 |
|---|---|
| author | Renaudeau, Julien Lidon, Pierre Salmon, Jean-Baptiste |
| author_facet | Renaudeau, Julien Lidon, Pierre Salmon, Jean-Baptiste |
| contents | We first highlight theoretically a microfluidic configuration that allows to measure two fundamental parameters describing mass transport through a membrane: the solute permeability coefficient $\mathcal{L}_D$, and the associated reflection coefficient $σ$. This configuration exploits the high confinement of microfluidic geometries to relate these two coefficients to the dynamics of a transient flow induced by forward osmosis through a membrane embedded in a chip. We then applied this methodology to hydrogel membranes photo-crosslinked in a microchannel with \textit{in situ} measurements of osmotically-induced flows. These experiments enable us to estimate $\mathcal{L}_D$ and $σ$ and their dependence on the molecular weight of the solute under consideration, ultimately leading to a precise estimate of the molecular weight cut-off of these hydrogel membranes. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2506_06186 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Transient osmotic flows in a microfluidic channel: measurements of solute permeability and reflection coefficients of hydrogel membranes Renaudeau, Julien Lidon, Pierre Salmon, Jean-Baptiste Soft Condensed Matter We first highlight theoretically a microfluidic configuration that allows to measure two fundamental parameters describing mass transport through a membrane: the solute permeability coefficient $\mathcal{L}_D$, and the associated reflection coefficient $σ$. This configuration exploits the high confinement of microfluidic geometries to relate these two coefficients to the dynamics of a transient flow induced by forward osmosis through a membrane embedded in a chip. We then applied this methodology to hydrogel membranes photo-crosslinked in a microchannel with \textit{in situ} measurements of osmotically-induced flows. These experiments enable us to estimate $\mathcal{L}_D$ and $σ$ and their dependence on the molecular weight of the solute under consideration, ultimately leading to a precise estimate of the molecular weight cut-off of these hydrogel membranes. |
| title | Transient osmotic flows in a microfluidic channel: measurements of solute permeability and reflection coefficients of hydrogel membranes |
| topic | Soft Condensed Matter |
| url | https://arxiv.org/abs/2506.06186 |